Evidence map›Paper›PMID 32163720›Full record

ReviewPhysiological reviews2020

Ion Channels Controlling Circadian Rhythms in Suprachiasmatic Nucleus Excitability.

Jenna R M Harvey, Amber E Plante, Andrea L Meredith

Open access · greenAbstract readReview
In one paragraph

Review in Physiological reviews, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 53 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
53citing papers in PubMed, 1 pooled it
6.5field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

53 citing papers in PubMed, 1 synthesis or guideline pooled it, 101 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Article
  5. Article
  6. A Subcircuit in the Suprachiasmatic Nucleus Generates Wakefulness.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025
    Article
  7. Review
  8. Review
  9. Physical activity stimulates clock neurons of the day-active rodentProceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  10. Article
  11. Article
  12. Review
  13. Article
  14. Review
  15. Article
  16. Article
  17. Progesterone activation of βNature communications · 2023
    Article
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Jenna R M HarveyDepartment of Physiology, University of Maryland School of Medicine, Baltimore, Maryland.
Amber E PlanteDepartment of Physiology, University of Maryland School of Medicine, Baltimore, Maryland.
Andrea L MeredithDepartment of Physiology, University of Maryland School of Medicine, Baltimore, Maryland.ORCID 0000-0003-1061-2302
University of Maryland, Baltimore · US

Funding

Daily Regulation of Ionic CurrentsR01HL102758 · NHLBI · UNIVERSITY OF MARYLAND BALTIMORE · PI LEDERER, WILLIAM JONATHAN · 2010 to 2024
$6.3M
TRAINING PROGRAM IN INTEGRATIVE MEMBRANE BIOLOGYT32GM008181 · NIGMS · UNIVERSITY OF MARYLAND BALTIMORE · PI RIZZO, MEGAN A, TRUDEAU, MATTHEW C · 1987 to 2022
$4.9M
NHLBI NIH HHS R01 HL102758NIGMS NIH HHS T32 GM008181
6 · The paper itself

Abstract

Animals synchronize to the environmental day-night cycle by means of an internal circadian clock in the brain. In mammals, this timekeeping mechanism is housed in the suprachiasmatic nucleus (SCN) of the hypothalamus and is entrained by light input from the retina. One output of the SCN is a neural code for circadian time, which arises from the collective activity of neurons within the SCN circuit and comprises two fundamental components:

Indexed as

AnimalsCircadian RhythmCLOCK ProteinsGene Expression RegulationIon ChannelsNeuronsSuprachiasmatic NucleusCLOCK ProteinsIon Channelsaction potentialcircadian rhythmexcitabilityion channelsuprachiasmatic nucleus

Identifiers

PMID32163720
PMCPMC7717126
OpenAlexW3011682897

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.