Evidence map›Paper›PMID 32167792›Full record

Trial reportJournal of child and adolescent psychopharmacology2020

Effects of Fish Oil Monotherapy on Depression and Prefrontal Neurochemistry in Adolescents at High Risk for Bipolar I Disorder: A 12-Week Placebo-Controlled Proton Magnetic Resonance Spectroscopy Trial.

Robert K McNamara, Jeffrey R Strawn, Max J Tallman, Jeffrey A Welge, L Rodrigo Patino, Thomas J Blom, Melissa P DelBello

Registry-linked trialOpen access · bronzeAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Journal of child and adolescent psychopharmacology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04844034 (The Effects of a High Eicosapentaenoic Acid Multinutrient Supplement on Measures of Stress, Anxiety and Depression in Young Adults), which is not on this map. Cited by 14 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 4 pooled it
1.8field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04844034 naunknown statusnot on this mapstarted 2022, after this paper: background citation

The Effects of a High Eicosapentaenoic Acid Multinutrient Supplement on Measures of Stress, Anxiety and Depression in Young Adults: a Randomised, Double-blind, Placebo-controlled Trial.

TypeinterventionalSponsorUniversity of RoehamptonRan2022 to 2023Enrolled94ConditionsAnxiety, DepressionArmsHigh-EPA multinutrient supplement., Placebo
3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 4 syntheses or guidelines pooled it, 23 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Nutraceuticals in Psychiatric Disorders: A Systematic Review.International journal of molecular sciences · 2024
    Pooled it
  4. Pooled it
  5. Trial
  6. Trial
  7. Review
  8. Review
  9. Review
  10. Omega-3 Polyunsaturated Fatty Acids in Depression.International journal of molecular sciences · 2024
    Review
  11. Review
  12. Article
  13. Review
  14. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Robert K McNamaraDivision of Bipolar Disorders Research, Department of Psychiatry and Behavioral Neuroscience, University of Cincinnati College of Medicine, Cincinnati, Ohio, USA.
Jeffrey R StrawnDivision of Bipolar Disorders Research, Department of Psychiatry and Behavioral Neuroscience, University of Cincinnati College of Medicine, Cincinnati, Ohio, USA.
Max J TallmanDivision of Bipolar Disorders Research, Department of Psychiatry and Behavioral Neuroscience, University of Cincinnati College of Medicine, Cincinnati, Ohio, USA.
Jeffrey A WelgeDivision of Bipolar Disorders Research, Department of Psychiatry and Behavioral Neuroscience, University of Cincinnati College of Medicine, Cincinnati, Ohio, USA.
L Rodrigo PatinoDivision of Bipolar Disorders Research, Department of Psychiatry and Behavioral Neuroscience, University of Cincinnati College of Medicine, Cincinnati, Ohio, USA.
Thomas J BlomDivision of Bipolar Disorders Research, Department of Psychiatry and Behavioral Neuroscience, University of Cincinnati College of Medicine, Cincinnati, Ohio, USA.
Melissa P DelBelloDivision of Bipolar Disorders Research, Department of Psychiatry and Behavioral Neuroscience, University of Cincinnati College of Medicine, Cincinnati, Ohio, USA.
University of Cincinnati Medical Center · US

Funding

Neurochemical Effects of Omega-3 Fatty Acids in Adolescents at Risk for ManiaR34MH083924 · NIMH · UNIVERSITY OF CINCINNATI · PI DELBELLO, MELISSA P, MCNAMARA, ROBERT K. · 2009 to 2011
$704k
NIMH NIH HHS R34 MH083924
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Proton Magnetic Resonance SpectroscopyAdolescentBipolar DisorderChildDouble-Blind MethodFatty Acids, Omega-3FemaleFish OilsGyrus CinguliHumansMajor Depressive DisorderMalePrefrontal CortexSeverity of Illness IndexTreatment OutcomeFatty Acids, Omega-3Fish Oilsadolescentbipolar disorderfamiliar riskMDDomega-3 polyunsaturated fatty acids

Identifiers

PMID32167792
PMCPMC7310320
OpenAlexW3010928787

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.