Evidence map›Paper›PMID 32172287›Full record

ArticleHistochemistry and cell biology2020

Plasma cells, plasmablasts, and AID

Birte S Steiniger, Linda Raimer, Anja Ecke, Boris A Stuck, Yalcin Cetin

Open access · hybridAbstract read
In one paragraph

Article in Histochemistry and cell biology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.1field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 20 citations in OpenAlex.

  1. Article
  2. Review
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  10. In focus in HCB.Histochemistry and cell biology · 2020
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Birte S SteinigerInstitute of Anatomy and Cell Biology, University of Marburg, Robert-Koch-Str. 8, 35037, Marburg, Germany. steinigb@staff.uni-marburg.de.
Linda RaimerInstitute of Anatomy and Cell Biology, University of Marburg, Robert-Koch-Str. 8, 35037, Marburg, Germany.
Anja EckeDepartment of Otorhinolaryngology, University Hospital Marburg, University of Marburg, Marburg, Germany.
Boris A StuckDepartment of Otorhinolaryngology, University Hospital Marburg, University of Marburg, Marburg, Germany.
Yalcin CetinInstitute of Anatomy and Cell Biology, University of Marburg, Robert-Koch-Str. 8, 35037, Marburg, Germany.
Philipps University of Marburg · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Plasma cells (PCs) in human palatine tonsils are predominantly located in the germinal centres (GCs), in the subepithelial space and near the deep connective tissue septa surrounding each crypt. We analysed the location, phenotype, and proliferation of GC PCs by immunohistology comparing them to PCs in the other two locations. Most PCs in GCs were strongly positive for CD38, CD138, CD27, IRF4, and intracellular (ic) IgG. They often accumulated in the basal light zone, but could also be found scattered in the entire light zone. In addition, rows of PCs occurred at the surface of the GC bordering the mantle zone, i.e., in the outer zone, and at the surface of the dark zone. The latter cells were often continuous with PCs in the extrafollicular area. The vast majority of GC PCs were negative for Ki-67. Only a few Ki-67

Indexed as

AICDA (Activation-Induced Cytidine Deaminase)B-LymphocytesCell ProliferationCytidine DeaminaseGerminal CenterHumansKi-1 AntigenPalatine TonsilPhenotypePlasma CellsAICDA (Activation-Induced Cytidine Deaminase)Cytidine DeaminaseKi-1 AntigenB lymphoblastsGerminal centresPalatine tonsilsPlasmablastsPlasma cells

Identifiers

PMID32172287
PMCPMC7343761
OpenAlexW3011036412

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.