Evidence map›Paper›PMID 32174776›Full record

ArticleInternational journal of medical sciences2020

Oxidative Stress Down-Regulates MiR-20b-5p, MiR-106a-5p and E2F1 Expression to Suppress the G1/S Transition of the Cell Cycle in Multipotent Stromal Cells.

Lihui Tai, Chiu-Jung Huang, Kong Bung Choo, Soon Keng Cheong, Tunku Kamarul

Open access · goldAbstract read
In one paragraph

Article in International journal of medical sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 41 citations in OpenAlex.

  1. Article
  2. Oxidative Stress and its Role in Carcinogenesis.Cell biochemistry and biophysics · 2026
    Review
  3. Article
  4. Article
  5. Article
  6. Review
  7. Review
  8. Review
  9. Article
  10. MiR-106a-5p by TargetingAnimals : an open access journal from MDPI · 2024
    Article
  11. Review
  12. Overview of miR-106a Regulatory Roles: from Cancer to Aging.Bioengineering (Basel, Switzerland) · 2023
    Review
  13. Review
  14. The dual role of microRNA (miR)-20b in cancers: Friend or foe?Cell communication and signaling : CCS · 2023
    Review
  15. Article
  16. Article
  17. Article
  18. Review
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 2 countries.

Lihui TaiCentre for Stem Cell Research, Faculty of Medicine and Health Sciences, Universiti Tunku Abdul Rahman, Selangor, Malaysia.
Chiu-Jung HuangDepartment of Animal Science & Graduate Institute of Biotechnology, Chinese Culture University, Taipei, Taiwan.
Kong Bung ChooCentre for Stem Cell Research, Faculty of Medicine and Health Sciences, Universiti Tunku Abdul Rahman, Selangor, Malaysia.
Soon Keng CheongCentre for Stem Cell Research, Faculty of Medicine and Health Sciences, Universiti Tunku Abdul Rahman, Selangor, Malaysia.
Tunku KamarulTissue Engineering Group, National Orthopedic Centre of Excellence for Research and Learning & Department of Orthopedic Surgery, Faculty of Medicine, Universiti Malaya, Kuala Lumpur, Malaysia.
Universiti Tunku Abdul Rahman · MYChinese Culture University · TWUniversity of Malaya · MY

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Oxidative stress has been linked to senescence and tumorigenesis via modulation of the cell cycle. Using a hydrogen peroxide (H

Indexed as

Blotting, WesternCell CycleCell LineE2F1 Transcription FactorHumansHydrogen PeroxideMicroRNAsOxidative StressReverse Transcriptase Polymerase Chain ReactionE2F1 protein, humanE2F1 Transcription FactorHydrogen PeroxideMicroRNAsMIRN106 microRNA, humanMIRN20b microRNA, humanE2F1G1/S transition of cell cyclemiR-17 familymiR-20b-5p & miR-106a-5poxidative stressp21/CDK/E2F1 pathway

Identifiers

PMID32174776
PMCPMC7053300
OpenAlexW3006314765

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.