Evidence map›Paper›PMID 32179671›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2020

CCAP regulates feeding behavior via the NPF pathway in

Michael J Williams, Mehwish Akram, Deimante Barkauskaite, Sourabh Patil, Eirini Kotsidou, Sania Kheder, Giovanni Vitale, Monica Filaferro, Simone W Blemings, Giulia Maestri and 3 more

Open access · bronzeAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
3.0field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 43 citations in OpenAlex.

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  15. Journal of developmental biology · 2021
    Review
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  19. Bilberry (Antioxidants (Basel, Switzerland) · 2020
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 2 institutions in 4 countries.

Michael J WilliamsFunctional Pharmacology, Department of Neuroscience, Uppsala University, 751 24 Uppsala, Sweden; michael.williams@neuro.uu.se.ORCID 0000-0003-4622-1207
Mehwish AkramFunctional Pharmacology, Department of Neuroscience, Uppsala University, 751 24 Uppsala, Sweden.
Deimante BarkauskaiteFunctional Pharmacology, Department of Neuroscience, Uppsala University, 751 24 Uppsala, Sweden.
Sourabh PatilFunctional Pharmacology, Department of Neuroscience, Uppsala University, 751 24 Uppsala, Sweden.ORCID 0000-0002-2784-2561
Eirini KotsidouFunctional Pharmacology, Department of Neuroscience, Uppsala University, 751 24 Uppsala, Sweden.
Sania KhederFunctional Pharmacology, Department of Neuroscience, Uppsala University, 751 24 Uppsala, Sweden.
Giovanni VitaleDepartment of Life Sciences, University of Modena and Reggio Emilia (RE), 41125 Modena, Italy.ORCID 0000-0002-4108-2861
Monica FilaferroDepartment of Biomedical, Metabolic and Neural Sciences, University of Modena and RE, 41125 Modena, Italy.
Simone W BlemingsFunctional Pharmacology, Department of Neuroscience, Uppsala University, 751 24 Uppsala, Sweden.
Giulia MaestriFunctional Pharmacology, Department of Neuroscience, Uppsala University, 751 24 Uppsala, Sweden.
Noor HazimFunctional Pharmacology, Department of Neuroscience, Uppsala University, 751 24 Uppsala, Sweden.
Anna Valeria VergoniDepartment of Biomedical, Metabolic and Neural Sciences, University of Modena and RE, 41125 Modena, Italy.ORCID 0000-0003-2580-4163
Helgi B SchiöthFunctional Pharmacology, Department of Neuroscience, Uppsala University, 751 24 Uppsala, Sweden.
Uppsala University · SEUniversity of Modena and Reggio Emilia · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The intake of macronutrients is crucial for the fitness of any animal and is mainly regulated by peripheral signals to the brain. How the brain receives and translates these peripheral signals or how these interactions lead to changes in feeding behavior is not well-understood. We discovered that 2 crustacean cardioactive peptide (CCAP)-expressing neurons in

Indexed as

AnimalsBrainCircadian RhythmDopamineDrosophila melanogasterDrosophila ProteinsFeeding BehaviorNeuronsNeuropeptidesSignal TransductionStarvationcrustacean cardioactive peptideDopamineDrosophila Proteinsneuropeptide FNeuropeptidesdopaminefeeding behaviorhypothalamusmetabolism

Identifiers

PMID32179671
PMCPMC7132124
OpenAlexW3012316157

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.