Evidence map›Paper›PMID 32185194›Full record

ArticleBioMed research international2020

Attenuation of Cortically Evoked Motor-Neuron Potential in Streptozotocin-Induced Diabetic Rats: A Study about the Effect of Diabetes upon Cortical-Initiated Movement.

Jesper Guldsmed Madsen, Jakob Appel Østergaard, Henning Andersen, Michael Pedersen

Open access · hybridAbstract read
In one paragraph

Article in BioMed research international, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.5field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Diabetes Mellitus-Related Dysfunction of the Motor System.International journal of molecular sciences · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Jesper Guldsmed MadsenComparativ Medicine Lab, Aarhus University Hospital, Aarhus, Denmark.ORCID https://orcid.org/0000-0002-7267-2418
Jakob Appel ØstergaardDepartment of Endocrinology and Diabetes, Aarhus University Hospital, Aarhus, Denmark.ORCID https://orcid.org/0000-0002-9877-5327
Henning AndersenDepartment of Neurology, Aarhus University Hospital, Aarhus, Denmark.
Michael PedersenComparativ Medicine Lab, Aarhus University Hospital, Aarhus, Denmark.ORCID https://orcid.org/0000-0002-1146-0382
Aarhus University Hospital · DKSteno Diabetes Centers · DK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

methodsIn this study, we investigated the cortical-evoked motor-neuron potentials in streptozotocin-induced diabetic rats. Cortical potentials were evoked using direct current stimulation to the motor cortex, and the resulting evoked potentials were recorded in the sciatic nerve. As voluntary movement consists of repeated activation of muscles, repeated stimulation trials were used to determine the effect of diabetes upon the animals' ability to recuperate between stimulations.

resultsOur findings showed that diabetes severely decreased the amplitude of cortical-evoked potentials and compromised the recuperation of motor neurons between activation.

Indexed as

AnimalsDiabetes Mellitus, ExperimentalDiabetic NeuropathiesEvoked Potentials, MotorFemaleMotor NeuronsMovementRatsRats, WistarSciatic NerveStreptozocinStreptozocin

Identifiers

PMID32185194
PMCPMC7061124
OpenAlexW3006692923

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.