Evidence map›Paper›PMID 32185685›Full record

ArticleJournal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology2021

Determinants of

Richard A P Takx, Ruth van Asperen, Jonas W Bartstra, Sabine R Zwakenberg, Jelmer M Wolterink, Csilla Celeng, Pim A de Jong, Joline W Beulens

Registry-linked trialOpen access · hybridAbstract read
In one paragraph

Article in Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02839044 (A Randomized, Placebo-controlled, Double Blind Trial to Investigate Whether Vitamin K2 Can Influence Arterial Calcification in Patients With Type 2 Diabetes), which is not on this map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
2.0field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02839044 nacompletednot on this map

A Randomized, Placebo-controlled, Double Blind Trial to Investigate Whether Vitamin K2 Can Influence Arterial Calcification in Patients With Type 2 Diabetes

TypeinterventionalSponsorUMC UtrechtRan2016 to 2018Enrolled68ConditionsArterial Calcification, Diabetes Mellitus Type 2ArmsMenaquinone-7, Placebo
3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 16 citations in OpenAlex.

  1. The international journal of cardiovascular imaging · 2025
    Article
  2. Review
  3. Review
  4. Article
  5. A longitudinal pilot study to assess temporal changes in coronary arterialJournal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2023
    Article
  6. Article
  7. Atherosclerosis Burdens in Diabetes Mellitus: Assessment by PET Imaging.International journal of molecular sciences · 2022
    Review
  8. PET-Based Imaging withDiagnostics (Basel, Switzerland) · 2021
    Review
  9. Article
  10. Review
  11. Advances in Quantitative Analysis ofMolecular imaging · 2021
    Review
  12. Atherosclerosis Imaging withDiagnostics (Basel, Switzerland) · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

Richard A P TakxDepartment of Radiology, University Medical Center Utrecht, Heidelberglaan 100, 3584 CX, Utrecht, The Netherlands. r.a.p.takx@umcutrecht.nl.
Ruth van AsperenDepartment of Radiology, University Medical Center Utrecht, Heidelberglaan 100, 3584 CX, Utrecht, The Netherlands.
Jonas W BartstraDepartment of Radiology, University Medical Center Utrecht, Heidelberglaan 100, 3584 CX, Utrecht, The Netherlands.
Sabine R ZwakenbergJulius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht, The Netherlands.
Jelmer M WolterinkImage Sciences Institute, University Medical Center Utrecht, Utrecht, The Netherlands.
Csilla CelengDepartment of Radiology, University Medical Center Utrecht, Heidelberglaan 100, 3584 CX, Utrecht, The Netherlands.
Pim A de JongDepartment of Radiology, University Medical Center Utrecht, Heidelberglaan 100, 3584 CX, Utrecht, The Netherlands.
Joline W BeulensDepartment of Epidemiology & Biostatistics, Amsterdam Public Health Research Institute, Vrije Universiteit, University Medical Center, Amsterdam, The Netherlands.
University Medical Center Utrecht · NLHeidelberg University · DEVrije Universiteit Amsterdam · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe goal of this study was to investigate the potential determinants of METHODS AND

resultsThe study consisted of participants of a randomized controlled trial to investigate the effect of vitamin K2 (NCT02839044). In this prespecified analysis, subjects with type 2 diabetes and known arterial disease underwent full body

conclusionThis study shows that several modifiable cardiovascular risk factors (total cholesterol, triglycerides, HbA1c) are associated with femoral

Indexed as

Diabetes Mellitus, Type 2Fluorine RadioisotopesSodium FluorideAgedDiabetic AngiopathiesFemaleFemoral ArteryHumansMaleMiddle AgedFluorine RadioisotopesSodium FluorideatherosclerosisCTdiabetesPADPET

Identifiers

PMID32185685
PMCPMC8709815
OpenAlexW3010924298

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.