Evidence map›Paper›PMID 32188115›Full record

ArticleViruses2020

Feline Parvovirus Seroprevalence Is High in Domestic Cats from Disease Outbreak and Non-Outbreak Regions in Australia.

Elizabeth Jenkins, Conor Davis, Maura Carrai, Michael P Ward, Susan O'Keeffe, Martine van Boeijen, Louise Beveridge, Costantina Desario, Canio Buonavoglia, Julia A Beatty and 2 more

Open access · goldAbstract read
In one paragraph

Article in Viruses, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
2.0field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 23 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 2 countries.

Elizabeth JenkinsSydney School of Veterinary Science, Faculty of Science, University of Sydney, Camperdown, NSW 2050, Australia.
Conor DavisSydney School of Veterinary Science, Faculty of Science, University of Sydney, Camperdown, NSW 2050, Australia.
Maura CarraiSydney School of Veterinary Science, Faculty of Science, University of Sydney, Camperdown, NSW 2050, Australia.
Michael P WardSydney School of Veterinary Science, Faculty of Science, University of Sydney, Camperdown, NSW 2050, Australia.
Susan O'KeeffeSchool of Veterinary and Life Sciences, Murdoch University, Murdoch, Western Australia 6150, Australia.
Martine van BoeijenPerth Cat Hospital, West Leederville, Western Australia 6007, Australia.
Louise BeveridgeBedford-Dianella Vet Centre, Bedford, Western Australia 6052, Australia.
Costantina DesarioDepartment of Veterinary Medicine, University of Bari, Valenzano, 70121 Bari, Italy.
Canio BuonavogliaDepartment of Veterinary Medicine, University of Bari, Valenzano, 70121 Bari, Italy.
Julia A BeattySydney School of Veterinary Science, Faculty of Science, University of Sydney, Camperdown, NSW 2050, Australia.ORCID 0000-0001-6520-7801
Nicola DecaroDepartment of Veterinary Medicine, University of Bari, Valenzano, 70121 Bari, Italy.ORCID 0000-0001-6348-7969
Vanessa R BarrsSydney School of Veterinary Science, Faculty of Science, University of Sydney, Camperdown, NSW 2050, Australia.
The University of Sydney · AUUniversity of Bari Aldo Moro · ITMurdoch University · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Multiple, epizootic outbreaks of feline panleukopenia (FPL) caused by feline parvovirus(FPV) occurred in eastern Australia between 2014 and 2018. Most affected cats were unvaccinated.We hypothesised that low population immunity was a major driver of re-emergent FPL. The aim ofthis study was to (i) determine the prevalence and predictors of seroprotective titres to FPV amongshelter-housed and owned cats, and (ii) compare the prevalence of seroprotection between a regionaffected and unaffected by FPL outbreaks. FPV antibodies were detected by haemagglutinationinhibition assay on sera from 523 cats and titres ≥1:40 were considered protective. Socioeconomicindices based on postcode and census data were included in the risk factor analysis. The prevalenceof protective FPV antibody titres was high overall (94.3%), even though only 42% of cats wereknown to be vaccinated, and was not significantly different between outbreak and non-outbreakregions. On multivariable logistic regression analysis vaccinated cats were 29.94 times more likelyto have protective FPV titres than cats not known to be vaccinated. Cats from postcodes of relativelyless socioeconomic disadvantage were 5.93 times more likely to have protective FPV titres. Thepredictors identified for FPV seroprotective titres indicate targeted vaccination strategies in regionsof socioeconomic disadvantage would be beneficial to increase population immunity. The criticallevel of vaccine coverage required to halt FPV transmission and prevent FPL outbreaks should bedetermined.

Indexed as

Disease OutbreaksAnimalsAntibodies, ViralAustraliaCatsFeline PanleukopeniaFeline Panleukopenia VirusFemaleMaleRegression AnalysisRisk FactorsSeroepidemiologic StudiesVaccinationViral VaccinesAntibodies, ViralViral VaccinesCarnivore protoparvovirusfeline panleukopeniafeline parvovirushaemagglutination inhibitionseroprevalence

Identifiers

PMID32188115
PMCPMC7150783
OpenAlexW3011082532

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.