Evidence map›Paper›PMID 32192015›Full record

ReviewCells2020

Impact of Chronic Fetal Hypoxia and Inflammation on Cardiac Pacemaker Cell Development.

Martin G Frasch, Dino A Giussani

Open access · goldAbstract readReview
In one paragraph

Review in Cells, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
1.0field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 14 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. [Characteristics of the left heart structure and function in 86 term neonates with intrauterine growth restriction].Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics · 2023
    Article
  5. Heart Rate Variability Code: Does It Exist and Can We Hack It?Bioengineering (Basel, Switzerland) · 2023
    Review
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 2 countries.

Martin G FraschDepartment of Obstetrics and Gynecology, University of Washington, Seattle, WA 98195, USA.ORCID 0000-0003-3159-6321
Dino A GiussaniDepartment of Physiology, Development & Neuroscience, University of Cambridge, Cambridge CB2 1TN, UK.ORCID 0000-0002-1308-1204
University of Cambridge · GBUniversity of Washington · US

Funding

Mechanisms of Brain Dysmorphology in MN1 C-Terminal Truncation Syndrome, a Novel Intellectual Developmental Disability Disorder P50HD103524 · NICHD · UNIVERSITY OF WASHINGTON · PI Sandra E Juul · 2020 to 2026
$9.9M
British Heart Foundation FS/12/74/29778British Heart Foundation RG/11/16/29260British Heart Foundation RG/17/8/32924NICHD NIH HHS P50 HD103524
6 · The paper itself

Abstract

Chronic fetal hypoxia and infection are examples of adverse conditions during complicated pregnancy, which impact cardiac myogenesis and increase the lifetime risk of heart disease. However, the effects that chronic hypoxic or inflammatory environments exert on cardiac pacemaker cells are poorly understood. Here, we review the current evidence and novel avenues of bench-to-bed research in this field of perinatal cardiogenesis as well as its translational significance for early detection of future risk for cardiovascular disease.

Indexed as

Cardiovascular DiseasesFetal HypoxiaHeartHumansHypoxiaInflammationRiskcardiac developmentfetal programmingiHRVintrinsic heart rate variabilitysinus node

Identifiers

PMID32192015
PMCPMC7140710
OpenAlexW3011772718

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.