Evidence map›Paper›PMID 32197378›Full record

ArticleViruses2020

Pervasive Differential Splicing in Marek's Disease Virus can Discriminate CVI-988 Vaccine Strain from RB-1B Very Virulent Strain in Chicken Embryonic Fibroblasts.

Yashar Sadigh, Abdessamad Tahiri-Alaoui, Stephen Spatz, Venugopal Nair, Paolo Ribeca

Open access · goldAbstract read
In one paragraph

Article in Viruses, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.9field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 8 citations in OpenAlex.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 2 countries.

Yashar SadighAvian Viral Oncogenesis, The Pirbright Institute, Ash Road, Woking GU24 0NF, UK.ORCID 0000-0003-1892-1361
Abdessamad Tahiri-AlaouiClinical BioManufacturing Facility, The Jenner Institute, University of Oxford, Old Road, Headington, Oxford OX3 7JT, UK.
Stephen SpatzUS National Poultry Research Center, 934 College Station Road, Athens, GA 30605, USA.
Venugopal NairAvian Viral Oncogenesis, The Pirbright Institute, Ash Road, Woking GU24 0NF, UK.ORCID 0000-0002-8255-516X
Paolo RibecaIntegrative Biology and Bioinformatics, The Pirbright Institute, Ash Road, Woking GU24 0NF, UK.ORCID 0000-0001-5599-3933
The Pirbright Institute · GBUniversity of Oxford · GBU.S. National Poultry Research Center · US

Funding

Biotechnology and Biological Sciences Research Council BB/E/I/00007035Biotechnology and Biological Sciences Research Council BB/E/I/00007036Biotechnology and Biological Sciences Research Council BB/K011057/1Biotechnology and Biological Sciences Research Council BBS/E/I/00001942Biotechnology and Biological Sciences Research Council BBS/E/I/00007034Biotechnology and Biological Sciences Research Council BBS/E/I/00007036Biotechnology and Biological Sciences Research Council BBS/E/I/00007039
6 · The paper itself

Abstract

Marek's disease is a major scourge challenging poultry health worldwide. It is caused by the highly contagious Marek's disease virus (MDV), an alphaherpesvirus. Here, we showed that, similar to other members of its

Indexed as

Gene Expression Regulation, ViralRNA SplicingAnimalsCell LineChick EmbryoComputational BiologyFibroblastsGene Expression ProfilingMardivirusMarek DiseaseSpecies SpecificityViral VaccinesVirulenceViral VaccinesMarek’s disease virusMDV strain CVI-988MDV strain RB-1BRNA splicing isoformstranscriptomics

Identifiers

PMID32197378
PMCPMC7150913
OpenAlexW3011911457

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.