Evidence mapPaperPMID 32197550Full record

ReviewInternational journal of molecular sciences2020

In Search for Genes Related to Atherosclerosis and Dyslipidemia Using Animal Models.

Anastasia V Poznyak, Andrey V Grechko, Reinhard Wetzker, Alexander N Orekhov

Open access · goldAbstract readReview
In one paragraph

Review in International journal of molecular sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.1field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 21 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Article
  5. Article
  6. Article
  7. Review
  8. Review
  9. Cardiac Mitochondria Dysfunction in Dyslipidemic Mice.International journal of molecular sciences · 2022
    Article
  10. Article
  11. Review
  12. Frontiers in cardiovascular medicine · 2021
    Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 4 institutions in 2 countries.

Anastasia V PoznyakInstitute for Atherosclerosis Research, Skolkovo Innovative Center, 121609 Moscow, Russia.
Andrey V GrechkoFederal Scientific Clinical Center for Resuscitation and Rehabilitation, 109240 Moscow, Russia.
Reinhard WetzkerDepartment of Anesthesiology and Intensive Care Medicine, Jena University Hospital, 07743 Jena, Germany.
Alexander N OrekhovLaboratory of Angiopathology, Institute of General Pathology and Pathophysiology, 125315 Moscow, Russia.ORCID 0000-0002-3318-4681
Institute for Atherosclerosis Research · RUJena University Hospital · DEResearch Institute of General Pathology and Pathophysiology, the Russian Academy of Medical Sciences · RUV.A. Negovsky Scientific Research Institute of General Reanimatology · RU

Funding

Russian Science Foundation 19-15-00010
6 · The paper itself

Abstract

Atherosclerosis is a multifactorial chronic disease that affects large arteries and may lead to fatal consequences. According to current understanding, inflammation and lipid accumulation are the two key mechanisms of atherosclerosis development. Animal models based on genetically modified mice have been developed to investigate these aspects. One such model is low-density lipoprotein (LDL) receptor knockout (KO) mice (

Indexed as

AtherosclerosisDyslipidemiasGene Expression RegulationAnimalsBiomarkersDisease Models, AnimalHumansMiceMice, KnockoutBiomarkersatherosclerosisepigeneticsmutations

Identifiers

PMID32197550
PMCPMC7139774
OpenAlexW3011019730

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.