Evidence map›Paper›PMID 32197774›Full record

ReviewSeminars in oncology2020

Current and coming challenges in the management of the survivorship population.

Eric J Chow, Kirsten K Ness, Gregory T Armstrong, Nickhill Bhakta, Jennifer M Yeh, Smita Bhatia, Wendy Landier, Louis S Constine, Melissa M Hudson, Paul C Nathan

Abstract readReview
In one paragraph

Review in Seminars in oncology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed.

  1. Trial
  2. Review
  3. Article
  4. Article
  5. Review
  6. Review of Paraneoplastic Syndromes in Children with Malignancy.Medical science monitor : international medical journal of experimental and clinical research · 2025
    Review
  7. Article
  8. Review
  9. Article
  10. Observational
  11. Article
  12. Cardio-Oncology in Childhood: State of the Art.Current oncology reports · 2022
    Review
  13. Article
  14. Article
  15. Living with the Late Effects of Childhood Cancer Treatment: A Descriptive Qualitative Study.International journal of environmental research and public health · 2021
    Article
  16. Observational
  17. Article
  18. Cancer treatment and survivorship statistics, 2025.CA: a cancer journal for clinicians
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Eric J ChowDivision of Clinical Research and Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, Washington; Department of Pediatrics, University of Washington, Seattle, Washington. Electronic address: ericchow@uw.edu.
Kirsten K NessDepartment of Epidemiology and Cancer Control, St. Jude Children's Research Hospital, Memphis, Tennessee.
Gregory T ArmstrongDepartment of Epidemiology and Cancer Control, St. Jude Children's Research Hospital, Memphis, Tennessee.
Nickhill BhaktaDepartment of Global Pediatric Medicine, St. Jude Children's Research Hospital, Memphis, Tennessee; Department of Oncology, St. Jude Children's Research Hospital, Memphis, Tennessee.
Jennifer M YehDivision of General Pediatrics, Boston Children's Hospital, Harvard Medical School, Boston, Massachusetts.
Smita BhatiaInstitute for Cancer Outcomes and Survivorship, University of Alabama at Birmingham, Birmingham, Alabama.
Wendy LandierInstitute for Cancer Outcomes and Survivorship, University of Alabama at Birmingham, Birmingham, Alabama.
Louis S ConstineDepartment of Radiation Oncology, University of Rochester Medical Center, Rochester, New York.
Melissa M HudsonDepartment of Epidemiology and Cancer Control, St. Jude Children's Research Hospital, Memphis, Tennessee; Department of Oncology, St. Jude Children's Research Hospital, Memphis, Tennessee.
Paul C NathanDivision of Hematology/Oncology, The Hospital for Sick Children, Toronto, Ontario, Canada.

Funding

NCTN BIQSFP ANBL1531 (NRT)U10CA180886 · NCI · PUBLIC HEALTH INSTITUTE · PI Douglas S. Hawkins · 2014 to 2026
$390.6M
Improving treatment of cardiovascular risk factors in childhood cancer survivorsR01CA204378 · NCI · FRED HUTCHINSON CANCER RESEARCH CENTER · PI CHOW, ERIC JESSEN · 2017 to 2021
$3.7M
NCI NIH HHS R01 CA204378NCI NIH HHS U10 CA180886
6 · The paper itself

Abstract

With the widespread adoption of multimodality treatment, 5-year survival of children diagnosed with cancer has improved dramatically in the past several decades from approximately 60% in 1970 to greater than 85% currently. As a result, there are an estimated nearly half a million long-term survivors of childhood cancer living in the United States today. However, survivors have, on average, significantly greater serious medical and psychosocial late effects compared with the general population. In this review, we will discuss the current epidemiology of childhood cancer survivorship, including new methods to estimate the burden of late effects and genetic susceptibility toward late effects. We will also review the development of surveillance guidelines for childhood cancer survivors and early toxicity signals from novel agents now being tested and used increasingly to treat pediatric and adult cancers. We conclude with an overview of current models of survivorship care and areas for future research.

Indexed as

Cancer SurvivorsSurvivorshipChildComorbidityCost of IllnessGenetic Predisposition to DiseaseHumansIncidenceNeoplasmsPublic Health SurveillanceQuality of LifeSocioeconomic Factors

Identifiers

PMID32197774
PMCPMC7227387

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.