Evidence map›Paper›PMID 32200490›Full record

ReviewCurrent pain and headache reports2020

A Comprehensive Review of the Treatment and Management of Pain in Sickle Cell Disease.

Jacob Fiocchi, Ivan Urits, Vwaire Orhurhu, Mariam Salisu Orhurhu, Stephen Giacomazzi, Briggs Hoyt, Alan D Kaye, Rachel J Kaye, Omar Viswanath

Abstract readReview
PubMed Publisher
In one paragraph

Review in Current pain and headache reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.0field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 15 citations in OpenAlex.

  1. Article
  2. Mathematical modeling of SCD: a literature review.Journal of sickle cell disease · 2025
    Review
  3. Article
  4. Review
  5. Pain management in the emergency department: a clinical review.Clinical and experimental emergency medicine · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 1 country.

Jacob FiocchiCreighton University School of Medicine, Phoenix Regional Campus, Phoenix, AZ, USA.
Ivan UritsDepartment of Anesthesia, Critical Care, and Pain Medicine, Beth Israel Deaconess Medical Center, Critical Care, and Pain Medicine, Harvard Medical School, 330 Brookline Ave, Boston, MA, 02215, USA. iurits@bidmc.harvard.edu.
Vwaire OrhurhuDepartment of Anesthesia, Critical Care, and Pain Medicine, Beth Israel Deaconess Medical Center, Critical Care, and Pain Medicine, Harvard Medical School, 330 Brookline Ave, Boston, MA, 02215, USA.
Mariam Salisu OrhurhuDepartment of Anesthesia, Critical Care, and Pain Medicine, Johns Hopkins Hospital, Baltimore, MD, USA.
Stephen GiacomazziCreighton University School of Medicine, Phoenix Regional Campus, Phoenix, AZ, USA.
Briggs HoytCreighton University School of Medicine, Phoenix Regional Campus, Phoenix, AZ, USA.
Alan D KayeDepartment of Anesthesiology, Louisiana State University Health Sciences Center, New Orleans, LA, USA.
Rachel J KayeDepartment of Anesthesiology, Louisiana State University Health Sciences Center, New Orleans, LA, USA.
Omar ViswanathValley Anesthesiology and Pain Consultants - Envision Physician Services, Phoenix, AZ, USA.
Creighton University · USHarvard University · USLouisiana State University Health Sciences Center New Orleans · USJohns Hopkins Hospital · USPhoenix (United States) · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purpose of reviewSickle cell disease (SCD) is a hematological disorder which leads to serious complications in multiple organ systems. While significant research has addressed many of the effects of acute pain episodes and end-organ damage connected to this disease, little has approached the chronic pain state associated with this condition. RECENT

findingsAssociated chronic pain represents a significant detractor from the quality of life experienced by these patients, affecting over half of those with SCD on more days than not. Current treatment typically is centered upon preventing and responding to acute vasoocclusive crises, presumably because this is the most common reason for hospitalization in these patients. The lack of management of chronic pain symptoms leaves many with SCD in a state of suffering. In this review, the treatment methodologies of SCD patients are examined including alternative treatments, both pharmaceutical and non-pharmaceutical, as well as procedural approaches specifically aimed at reducing chronic pain in these patients.

Indexed as

Anemia, Sickle CellChronic PainHumansPain ManagementChronic painCognitive behavioral therapySickle cell diseaseVasoocclusive crisis

Identifiers

PMID32200490
OpenAlexW3012866126

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.