Evidence map›Paper›PMID 32204385›Full record

ArticleAnimals : an open access journal from MDPI2020

Hepatic Inflammatory Response to Exogenous LPS Challenge is Exacerbated in Broilers with Fatty Liver Disease.

Wenqing Mei, Yarong Hao, Huilin Xie, Yingdong Ni, Ruqian Zhao

Open access · goldAbstract read
In one paragraph

Article in Animals : an open access journal from MDPI, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
1.5field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 24 citations in OpenAlex.

  1. Article
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  6. Microorganisms · 2024
    Review
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  11. Article
  12. Frontiers in veterinary science · 2022
    Article
  13. Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Wenqing MeiKey Laboratory of Animal Physiology & Biochemistry, Nanjing Agricultural University, Nanjing 210095, China.
Yarong HaoKey Laboratory of Animal Physiology & Biochemistry, Nanjing Agricultural University, Nanjing 210095, China.
Huilin XieKey Laboratory of Animal Physiology & Biochemistry, Nanjing Agricultural University, Nanjing 210095, China.
Yingdong NiKey Laboratory of Animal Physiology & Biochemistry, Nanjing Agricultural University, Nanjing 210095, China.
Ruqian ZhaoKey Laboratory of Animal Physiology & Biochemistry, Nanjing Agricultural University, Nanjing 210095, China.
Nanjing Agricultural University · CN

Funding

National Key R&D Program of China 2017YFE0114400
6 · The paper itself

Abstract

This study aimed to examine hepatic function and inflammatory response in broilers with fatty livers, following acute lipopolysaccharide (LPS) challenge. One-day-old Lihua yellow broilers were fed a basal diet. Broilers were divided into four groups: control (CON), corticosterone treatment (CORT), LPS treatment (LPS), and LPS and CORT treatment (LPS&CORT). Results show that CORT induced an increase in plasma and liver triglycerides (TGs), which were accompanied by severe hepatic steatosis. The LPS group showed hepatocyte necrosis with inflammatory cell infiltration. Total liver damage score in the LPS&CORT group was significantly higher than that in the LPS group (

Indexed as

broilercorticosteronefatty liverinflammationLPS

Identifiers

PMID32204385
PMCPMC7143745
OpenAlexW3012479021

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.