Evidence map›Paper›PMID 32213600›Full record

ArticleThe Journal of biological chemistry2020

Impact of 1,

Pratibha P Ghodke, F Peter Guengerich

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in The Journal of biological chemistry, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.5field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. DNA polymerases η and κ bypass NThe Journal of biological chemistry · 2021
    Article
  3. Etheno adducts: from tRNA modifications to DNA adducts and back to miscoding ribonucleotides.Genes and environment : the official journal of the Japanese Environmental Mutagen Society · 2021
    Review
  4. Enzymatic bypass of an NThe Journal of biological chemistry
    Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Pratibha P GhodkeDepartment of Biochemistry, Vanderbilt University School of Medicine, Nashville, Tennessee 37323-0146.
F Peter GuengerichDepartment of Biochemistry, Vanderbilt University School of Medicine, Nashville, Tennessee 37323-0146. Electronic address: f.guengerich@vanderbilt.edu.
Vanderbilt University · US

Funding

Mechanisms of Copying of Carcinogen-damaged DNA and RNA by Translesion PolymerasesR01ES026955 · NIEHS · VANDERBILT UNIVERSITY · PI GUENGERICH, F PETER · 2017 to 2021
$1.8M
NIEHS NIH HHS R01 ES026955
6 · The paper itself

Abstract

Incorporation of ribonucleotides into DNA can severely diminish genome integrity. However, how ribonucleotides instigate DNA damage is poorly understood. In DNA, they can promote replication stress and genomic instability and have been implicated in several diseases. We report here the impact of the ribonucleotide rATP and of its naturally occurring damaged analog 1,

Indexed as

DNA DamageDNA RepairAdenosineAdenosine TriphosphateDNA-Directed DNA PolymeraseDNA ReplicationGuanosine TriphosphateHumansRibonuclease HY-Family DNA Polymerases1,N(6)-ethenoadenosineAdenosineAdenosine TriphosphateDNA-Directed DNA PolymeraseGuanosine TriphosphateRad30 proteinRibonuclease Hribonuclease HIIY-Family DNA Polymerases1,N6-ethenoadenosine (1,N6-εrA)DNA adductsDNA alkylationDNA damageDNA enzymeDNA polymerasegenome integritypolymerase etareverse transcriptionRNA modificationRNA processingtranslesion synthesis (TLS)

Identifiers

PMID32213600
PMCPMC7196658
OpenAlexW3013513430

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.