ArticleScientific reports2020
The transcriptome of the newt Cynops orientalis provides new insights into evolution and function of sexual gene networks in sarcopterygians.
Article in Scientific reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed, 19 citations in OpenAlex.
- Molecular Mechanisms of Gonadal Differentiation Induced by 17β-Estradiol and Testosterone Propionate inAnimals : an open access journal from MDPI · 2026Article
- Genomic selection and association analyses for improving semen traits in Thai native roosters.Poultry science · 2026Article
- Heat shock protein 70 in Cynops orientalis: bidirectional thermal regulation and metabolic optimization in amphibian climatic adaptation.BMC genomics · 2026Article
- Sex- and stage-dependent expression of gonadal soma-derived factor paralogues reveals functional and evolutionary divergence in European sea bass (Frontiers in endocrinology · 2026Article
- Trunk muscle differentiation-a lesson from the Chinese fire-bellied newt (Hypselotriton orientalis).Protoplasma · 2025Article
- A bioinformatic approach to characterize the vitellogenin receptor and the low density lipoprotein receptor superfamily in the newt Cynops orientalis.Scientific reports · 2025Article
- Rebuilding limbs, one cell at a time.Developmental dynamics : an official publication of the American Association of Anatomists · 2022Article
- The vitellogenin genes in Cynops orientalis: New insights on the evolution of the vtg gene family in amphibians.Journal of experimental zoology. Part B, Molecular and developmental evolution · 2021Article
- A brief review of vertebrate sex evolution with a pledge for integrative research: towards 'Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2021Review
- The replaceable master of sex determination: bottom-up hypothesis revisited.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2021Review
- Investigation of the activity of transposable elements and genes involved in their silencing in the newt Cynops orientalis, a species with a giant genome.Scientific reports · 2021Article
- Review
- Transcriptomic analysis of gonadal development in parasitic and non-parasitic lampreys (Ichthyomyzon spp.), with a comparison of genomic resources in these non-model species.G3 (Bethesda, Md.) · 2021Article
- Evolution, Expression, and Function of Gonadal Somatic Cell-Derived Factor.Frontiers in cell and developmental biology · 2021Review
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8 authors at 3 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Amphibians evolved in the Devonian period about 400 Mya and represent a transition step in tetrapod evolution. Among amphibians, high-throughput sequencing data are very limited for Caudata, due to their largest genome sizes among terrestrial vertebrates. In this paper we present the transcriptome from the fire bellied newt Cynops orientalis. Data here presented display a high level of completeness, comparable to the fully sequenced genomes available from other amphibians. Moreover, this work focused on genes involved in gametogenesis and sexual development. Surprisingly, the gsdf gene was identified for the first time in a tetrapod species, so far known only from bony fish and basal sarcopterygians. Our analysis failed to isolate fgf24 and foxl3, supporting the possible loss of both genes in the common ancestor of Rhipidistians. In Cynops, the expression analysis of genes described to be sex-related in vertebrates singled out an expected functional role for some genes, while others displayed an unforeseen behavior, confirming the high variability of the sex-related pathway in vertebrates.
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