Evidence map›Paper›PMID 32215284›Full record

ArticleBone reports2020

No evidence for alteration in early secondary mineralization by either alendronate, teriparatide or combination of both in transiliac bone biopsy samples from postmenopausal osteoporotic patients.

Barbara M Misof, Paul Roschger, Hua Zhou, Jeri W Nieves, Mathias Bostrom, Felicia Cosman, Robert Lindsay, Klaus Klaushofer, David W Dempster

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Bone reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
1.2field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 10 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Review
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 2 countries.

Barbara M MisofLudwig Boltzmann Institute of Osteology at Hanusch Hospital of OEGK and AUVA Trauma Centre Meidling, 1st Med. Dept. Hanusch Hospital, Vienna, Austria.
Paul RoschgerLudwig Boltzmann Institute of Osteology at Hanusch Hospital of OEGK and AUVA Trauma Centre Meidling, 1st Med. Dept. Hanusch Hospital, Vienna, Austria.
Hua ZhouRegional Bone Center and Clinical Research Center, Helen Hayes Hospital, West Haverstraw, NY, USA.
Jeri W NievesDepartment of Epidemiology, Columbia University, New York, NY, USA.
Mathias BostromRegional Bone Center and Clinical Research Center, Helen Hayes Hospital, West Haverstraw, NY, USA.
Felicia CosmanDepartment of Medicine, Columbia University, New York, NY, USA.
Robert LindsayRegional Bone Center and Clinical Research Center, Helen Hayes Hospital, West Haverstraw, NY, USA.
Klaus KlaushoferLudwig Boltzmann Institute of Osteology at Hanusch Hospital of OEGK and AUVA Trauma Centre Meidling, 1st Med. Dept. Hanusch Hospital, Vienna, Austria.
David W DempsterRegional Bone Center and Clinical Research Center, Helen Hayes Hospital, West Haverstraw, NY, USA.
Hanusch Hospital · ATHelen Hayes Hospital · USHospital for Special Surgery · USColumbia University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The influence of treatment with alendronate (ALN), teriparatide (TPTD) or concurrent treatment with both on the human bone matrix mineralization has not yet been fully elucidated. For this purpose we analyzed quadruple fluorochrome labelled transiliac bone biopsy samples (

Indexed as

Bone matrix mineralizationCombined therapy with alendronate and teriparatideQuadruple labellingSecondary mineralizationTransiliac bone biopsy

Identifiers

PMID32215284
PMCPMC7090359
OpenAlexW3007694868

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.