Evidence map›Paper›PMID 32218991›Full record

ArticleNPJ Regenerative medicine2020

A subset of SMN complex members have a specific role in tissue regeneration via ERBB pathway-mediated proliferation.

Wuhong Pei, Lisha Xu, Zelin Chen, Claire C Slevin, Kade P Pettie, Stephen Wincovitch, NISC Comparative Sequencing Program, Shawn M Burgess

Open access · goldAbstract read
In one paragraph

Article in NPJ Regenerative medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.3field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 18 citations in OpenAlex.

  1. Article
  2. CRISPR-based functional genomics tools in vertebrate models.Experimental & molecular medicine · 2025
    Review
  3. Article
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  12. Emerging Roles of Gemin5: From snRNPs Assembly to Translation Control.International journal of molecular sciences · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Wuhong Pei1Translational and Functional Genomics Branch, National Human Genome Research Institute, Bethesda, MD 20892 USA.
Lisha Xu1Translational and Functional Genomics Branch, National Human Genome Research Institute, Bethesda, MD 20892 USA.
Zelin Chen1Translational and Functional Genomics Branch, National Human Genome Research Institute, Bethesda, MD 20892 USA.
Claire C Slevin1Translational and Functional Genomics Branch, National Human Genome Research Institute, Bethesda, MD 20892 USA.
Kade P Pettie1Translational and Functional Genomics Branch, National Human Genome Research Institute, Bethesda, MD 20892 USA.ORCID 0000-0001-8445-3928
Stephen Wincovitch2Cytogenetics and Microscopy Core, National Human Genome Research Institute, Bethesda, MD 20892 USA.
NISC Comparative Sequencing Program
Shawn M Burgess1Translational and Functional Genomics Branch, National Human Genome Research Institute, Bethesda, MD 20892 USA.ORCID 0000-0003-1147-0596
National Institutes of Health · USNational Human Genome Research Institute · US

Funding

Inter- and Intra-Species Comparative SequencingZIBHG000196 · NHGRI · NATIONAL HUMAN GENOME RESEARCH INSTITUTE · PI THOMAS, JAMES · 2009 to 2025
$177.6M
Hearing regeneration in zebrafishZIAHG200386 · NHGRI · NATIONAL HUMAN GENOME RESEARCH INSTITUTE · PI BURGESS, SHAWN M · 2012 to 2025
$12.5M
Intramural NIH HHS ZIA HG200386
6 · The paper itself

Abstract

Spinal muscular atrophy (SMA) is the most common genetic disease in children. SMA is generally caused by mutations in the gene

Indexed as

GeneticsRegeneration

Identifiers

PMID32218991
PMCPMC7096462
OpenAlexW3014056864

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.