Evidence map›Paper›PMID 32226526›Full record

ArticleTheranostics2020

A novel function of Prohibitin on melanosome transport in melanocytes.

Chan Song Jo, Hye In Park, Hyun Jin Jung, Jong Il Park, Ji Eun Lee, Cheol Hwan Myung, Jae Sung Hwang

Open access · goldAbstract read
In one paragraph

Article in Theranostics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
1.6field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 24 citations in OpenAlex.

  1. Article
  2. Article
  3. Disrupting melanin transfer: innovative strategy for anti-pigmentation drug discovery.Journal of enzyme inhibition and medicinal chemistry · 2025
    Review
  4. Review
  5. Article
  6. An Overview of the Biological Complexity of Vitiligo.Oxidative medicine and cellular longevity · 2024
    Review
  7. Article
  8. Review
  9. Article
  10. Article
  11. Review
  12. Article
  13. Article
  14. PHB2 promotes tumorigenesisTheranostics · 2021
    Article
  15. A ThirdGenes · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Chan Song JoDepartment of Genetic Engineering & Graduate School of Biotechnology, College of Life Sciences, Kyung Hee University, Yongin, Gyeonggi-do 446-701, Republic of Korea.
Hye In ParkDepartment of Genetic Engineering & Graduate School of Biotechnology, College of Life Sciences, Kyung Hee University, Yongin, Gyeonggi-do 446-701, Republic of Korea.
Hyun Jin JungDepartment of Genetic Engineering & Graduate School of Biotechnology, College of Life Sciences, Kyung Hee University, Yongin, Gyeonggi-do 446-701, Republic of Korea.
Jong Il ParkDepartment of Genetic Engineering & Graduate School of Biotechnology, College of Life Sciences, Kyung Hee University, Yongin, Gyeonggi-do 446-701, Republic of Korea.
Ji Eun LeeDepartment of Genetic Engineering & Graduate School of Biotechnology, College of Life Sciences, Kyung Hee University, Yongin, Gyeonggi-do 446-701, Republic of Korea.
Cheol Hwan MyungDepartment of Genetic Engineering & Graduate School of Biotechnology, College of Life Sciences, Kyung Hee University, Yongin, Gyeonggi-do 446-701, Republic of Korea.
Jae Sung HwangDepartment of Genetic Engineering & Graduate School of Biotechnology, College of Life Sciences, Kyung Hee University, Yongin, Gyeonggi-do 446-701, Republic of Korea.
Kyung Hee University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Prohibitin (PHB, also known as PHB1 or BAP32), is a highly conserved 31kDa protein that expressed in many cellular compartments, such as mitochondria, nucleus, cytosol, and plasma membrane, and plays roles in regulating the transcription of genes, apoptosis, and mitochondrial biogenesis. There is a report that Prohibitin expression is required for the stimulation of pigmentation by melanogenin. However, no studies have been published on the function of PHB in melanocytes, especially in melanosome transport.

Indexed as

Adaptor Proteins, Signal TransducingAnimalsBiological TransportCells, CulturedMelaninsMelanosomesMiceMice, Inbred C57BLPigmentationProhibitinsProtein Bindingrab27 GTP-Binding ProteinsRepressor ProteinsAdaptor Proteins, Signal TransducingMelaninsMlph protein, mouseProhibitinsRab27a protein, mouserab27 GTP-Binding ProteinsRepressor ProteinsMelanophilinmelanosome transportProhibitinRab27a

Identifiers

PMID32226526
PMCPMC7086355
OpenAlexW3012751591

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.