Evidence map›Paper›PMID 32226550›Full record

ArticleTheranostics2020

Loss of EGR-1 uncouples compensatory responses of pancreatic β cells.

Sy-Ying Leu, Li-Hua Kuo, Wen-Tsan Weng, I-Chia Lien, Ching-Chun Yang, Tai-Tzu Hsieh, Yi-Ning Cheng, Po-Hsiu Chien, Li-Chun Ho, Shun-Hua Chen and 5 more

Open access · goldAbstract read
In one paragraph

Article in Theranostics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
3.1field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 14 citations in OpenAlex.

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  8. International journal of molecular sciences · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 3 institutions in 1 country.

Sy-Ying LeuInstitute of Clinical Medicine, College of Medicine, National Cheng Kung University, Taiwan, ROC.
Li-Hua KuoInstitute of Clinical Medicine, College of Medicine, National Cheng Kung University, Taiwan, ROC.
Wen-Tsan WengInstitute of Clinical Medicine, College of Medicine, National Cheng Kung University, Taiwan, ROC.
I-Chia LienInstitute of Clinical Medicine, College of Medicine, National Cheng Kung University, Taiwan, ROC.
Ching-Chun YangInstitute of Clinical Medicine, College of Medicine, National Cheng Kung University, Taiwan, ROC.
Tai-Tzu HsiehInstitute of Clinical Medicine, College of Medicine, National Cheng Kung University, Taiwan, ROC.
Yi-Ning ChengInstitute of Clinical Medicine, College of Medicine, National Cheng Kung University, Taiwan, ROC.
Po-Hsiu ChienDepartment of Physiology, College of Medicine, National Cheng Kung University, Taiwan, ROC.
Li-Chun HoInstitute of Clinical Medicine, College of Medicine, National Cheng Kung University, Taiwan, ROC.
Shun-Hua ChenDepartment of Microbiology and Immunology, College of Medicine, National Cheng Kung University, Taiwan, ROC.
Yan-Shen ShanInstitute of Clinical Medicine, College of Medicine, National Cheng Kung University, Taiwan, ROC.
Yun-Wen ChenDepartment of Pharmacology, College of Medicine, National Cheng Kung University, Taiwan, ROC.
Pei-Jane TsaiDepartment of Medical Laboratory Science and Biotechnology, College of Medicine, National Cheng Kung University, Taiwan, ROC.
Junne-Ming SungDivision of Nephrology, Department of Internal Medicine, National Cheng Kung University Hospital, Tainan, Taiwan, ROC.
Yau-Sheng TsaiInstitute of Clinical Medicine, College of Medicine, National Cheng Kung University, Taiwan, ROC.
National Cheng Kung University Hospital · TWI-Shou University · TWNational Cheng Kung University · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AnimalsCell Line, TumorDiabetes Mellitus, Type 2Early Growth Response Protein 1GlucagonGlucoseInsulinInsulin-Secreting CellsMaleMiceMice, Inbred C57BLMice, KnockoutEarly Growth Response Protein 1Egr1 protein, mouseGlucagonGlucoseInsulinimmediate genesislet failurestimulus-response couplingβ-cell compensationβ-cell identity

Identifiers

PMID32226550
PMCPMC7086362
OpenAlexW3012830172

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.