Evidence map›Paper›PMID 32228173›Full record

ArticleUnited European gastroenterology journal2020

Functional dyspepsia is associated with lower exercise levels: A population-based study.

Natasha A Koloski, Michael Jones, Marjorie M Walker, Gerald Holtmann, Nicholas J Talley

Abstract read
In one paragraph

Article in United European gastroenterology journal, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Physical Activity as a Therapeutic Strategy for Functional Dyspepsia.Journal of neurogastroenterology and motility · 2026
    Article
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  8. Review
  9. Circadian regulation of gastrointestinal motility and the effect on disorders of gut-brain interaction.Journal of smooth muscle research = Nihon Heikatsukin Gakkai kikanshi · 2026
    Review
  10. Clinical Relevance of Gastric Emptying Time in Functional Dyspepsia.Journal of neurogastroenterology and motility · 2025
    Article
  11. Article
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  15. A comprehensive review of functional dyspepsia in pediatrics.Clinical journal of gastroenterology · 2022
    Review
  16. Article
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Natasha A KoloskiFaculty of Health and Medicine, University of Newcastle, Callaghan, Australia.
Michael JonesDepartment of Psychology, Macquarie University, Ryde, Australia.ORCID 0000-0003-0565-4938
Marjorie M WalkerFaculty of Health and Medicine, University of Newcastle, Callaghan, Australia.
Gerald HoltmannDepartment of Gastroenterology and Hepatology, Princess Alexandra Hospital, Brisbane, Australia.
Nicholas J TalleyFaculty of Health and Medicine, University of Newcastle, Callaghan, Australia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundExercise improves symptoms of irritable bowel syndrome, but few data are available about functional dyspepsia. We compared the prevalence and frequency of different types of exercise between individuals with functional dyspepsia and general population controls.

methodsA mailed survey was returned by 3160 people randomly obtained from the Australian electoral register. The survey included questions to identify the Rome III diagnosis for functional dyspepsia. Exercise was classified by the presence (yes or no) and the frequency (number of times) spent walking, and engaging in moderate and vigorous exercise, over the last 2 weeks based on the National Health Survey. Controls did not meet criteria for functional dyspepsia. Potential confounders included the presence of irritable bowel syndrome, smoking, body mass index, age and gender.

resultsA total of 14.8% (95% confidence interval (CI) 13.6%, 16.1%) subjects had functional dyspepsia. They reported significantly less walking (57% versus 63%, P = 0.04) and lower frequency of exercising, in terms of walking (P = 0.008) and engaging in moderate (P = 0.03) and vigorous activity (P = 0.02), compared with controls. The association remained significant for moderate exercise, independent of age, gender, body mass index and smoking, and excluding overlap with irritable bowel syndrome (odds ratio (OR) = 0.94 (95% CI 0.88, 0.99), P = 0.02). Postprandial distress syndrome was associated with less-vigorous exercise adjusting for confounders (OR = 0.65 (95% CI 0.42, 1.0), P = 0.05), but not epigastric pain syndrome.

conclusionFunctional dyspepsia is associated with lower exercise levels, but the causality still needs to be determined.

Indexed as

AdultAgedAustraliaCase-Control StudiesCausalityDyspepsiaExerciseFemaleHealth SurveysHumansMaleMiddle AgedOdds RatioPrevalenceRisk FactorsSelf ReportEpidemiologyfunctional dyspepsiairritable bowel syndromelifestylephysical activity

Identifiers

PMID32228173
PMCPMC7268935

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.