Evidence map›Paper›PMID 32230987›Full record

Trial reportNutrients2020

Randomised Double-Blind Placebo-Controlled Trial of Inulin with Metronidazole in Non-Alcoholic Fatty Liver Disease (NAFLD).

Clara Yieh Lin Chong, David Orr, Lindsay D Plank, Tommi Vatanen, Justin M O'Sullivan, Rinki Murphy

Registry-linked trialOpen access · goldAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Nutrients, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05885373 (A Single-arm, Open-label Clinical Study to Evaluate the Effect of SIM01 in Female Subjects With Non-Alcoholic Fatty Liver Disease), which is not on this map. Cited by 38 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
38citing papers in PubMed, 3 pooled it
5.4field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05885373 nacompletednot on this mapstarted 2023, after this paper: background citation

A Single-arm, Open-label Clinical Study to Evaluate the Effect of SIM01 in Female Subjects With Non-Alcoholic Fatty Liver Disease (NAFLD)

TypeinterventionalSponsorGenieBiome LimitedRan2023 to 2023Enrolled40ConditionsNon-Alcoholic Fatty Liver DiseaseArmsSIM01
3 · Its place in the literature

Who cites it

38 citing papers in PubMed, 3 syntheses or guidelines pooled it, 61 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Trial
  5. Trial
  6. Review
  7. Review
  8. AnIranian journal of basic medical sciences · 2026
    Article
  9. Review
  10. Review
  11. Review
  12. Article
  13. Review
  14. Review
  15. Review
  16. Article
  17. Article
  18. Review
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Clara Yieh Lin ChongLiggins Institute, The University of Auckland, Auckland 1142, New Zealand.ORCID 0000-0001-6796-9914
David OrrNew Zealand Liver Transplant Unit, Auckland City Hospital, Auckland 1023, New Zealand.
Lindsay D PlankDepartment of Surgery, Faculty of Medical and Health Sciences, The University of Auckland, Auckland 1142, New Zealand.ORCID 0000-0003-2737-0151
Tommi VatanenLiggins Institute, The University of Auckland, Auckland 1142, New Zealand.ORCID 0000-0003-0949-1291
Justin M O'SullivanLiggins Institute, The University of Auckland, Auckland 1142, New Zealand.ORCID 0000-0003-2927-450X
Rinki MurphyDepartment of Medicine, Faculty of Medical and Health Sciences, The University of Auckland, Auckland 1142, New Zealand.
University of Auckland · NZAuckland City Hospital · NZ

Funding

New Zealand Society for Gastroenterology A+ Trust
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Non-alcoholic Fatty Liver DiseaseAdultAgedAlanine TransaminaseAnti-Infective AgentsCaloric RestrictionDouble-Blind MethodFecesFemaleGastrointestinal MicrobiomeHumansInulinMaleMetronidazoleMiddle AgedPrebioticsAlanine TransaminaseAnti-Infective AgentsInulinMetronidazolePrebioticsalanine aminotransferaseantibioticgut microbiomeinulinmetronidazoleOptifastprebiotics

Identifiers

PMID32230987
PMCPMC7230525
OpenAlexW3013363880

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.