Evidence mapPaperPMID 32235534Full record

ArticleMolecules (Basel, Switzerland)2020

Antioxidant Potential of Antiviral Drug Umifenovir.

Elena V Proskurnina, Dmitry Yu Izmailov, Madina M Sozarukova, Tatiana A Zhuravleva, Irina A Leneva, Artem A Poromov

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
6.2field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 53 citations in OpenAlex.

  1. Article
  2. Advancements in the development of antivirals against SARS-Coronavirus.Frontiers in cellular and infection microbiology · 2025
    Review
  3. Review
  4. Article
  5. Pharmaceuticals (Basel, Switzerland) · 2024
    Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Review
  11. Antioxidant Potential of Aqueous Dispersions of Fullerenes CInternational journal of molecular sciences · 2021
    Article
  12. Review
  13. Article
  14. Article
  15. Review
  16. Wuhan to World: The COVID-19 Pandemic.Frontiers in cellular and infection microbiology · 2021
    Review
  17. Review
  18. Review
  19. Review
  20. Umifenovir treatment is not associated with improved outcomes in patients with coronavirus disease 2019: a retrospective study.Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 1 country.

Elena V ProskurninaResearch Centre for Medical Genetics, ul. Moskvorechye 1, Moscow115522, Russia.ORCID 0000-0002-8243-6339
Dmitry Yu IzmailovFaculty of Fundamental Medicine, Lomonosov Moscow State University, Lomonosovsky prospekt 27-1, Moscow 119234, Russia.
Madina M SozarukovaKurnakov Institute of General and Inorganic Chemistry, Russian Academy of Sciences, Leninsky prospekt 31, Moscow 119991, Russia.
Tatiana A ZhuravlevaFaculty of Fundamental Medicine, Lomonosov Moscow State University, Lomonosovsky prospekt 27-1, Moscow 119234, Russia.
Irina A LenevaDepartment of Experimental Virology, Mechnikov Research Institute for Vaccines and Sera, Malyi Kazennyi pereulok 5a, Moscow105064, Russia.
Artem A PoromovDepartment of Experimental Virology, Mechnikov Research Institute for Vaccines and Sera, Malyi Kazennyi pereulok 5a, Moscow105064, Russia.
Lomonosov Moscow State University · RUResearch Institute of Vaccines and Sera. Mechnikov of the Russian Academy of Medical Sciences · RUNS Kurnakova Institute of General and Inorganic Chemistry · RUResearch Centre for Medical Genetics · RU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Free radical reactions play an important role in biological functions of living systems. The balance between oxidants and antioxidants is necessary for the normal homeostasis of cells and organisms. Experimental works demonstrate the role of oxidative stress that is caused by influenza virus as well as the toxic effects of some antiviral drugs. Therefore, antiviral drugs should be characterized by its pro- and antioxidant activity, because it can affect its therapeutic efficiency. The aim of the study was to quantify the antioxidant capacity and propose the mechanism of the antioxidant effect of the antiviral drug Umifenovir (Arbidol

Indexed as

Computer SimulationModels, ChemicalAntioxidantsAntiviral AgentsIndolesKineticsSulfidesAntioxidantsAntiviral AgentsIndolesSulfidesumifenovirantioxidant potentialkinetic chemiluminometryUmifenovir

Identifiers

PMID32235534
PMCPMC7181215
OpenAlexW3014016658

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.