Evidence map›Paper›PMID 32235787›Full record

ReviewInternational journal of molecular sciences2020

The Current Genomic and Molecular Landscape of Philadelphia-like Acute Lymphoblastic Leukemia.

Parveen Shiraz, Kimberly J Payne, Lori Muffly

Abstract readReview
In one paragraph

Review in International journal of molecular sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed.

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  19. Frontiers in cell and developmental biology · 2022
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Parveen ShirazDivision of Blood and Marrow Transplantation, Stanford University, Stanford, CA 94305, USA.ORCID 0000-0002-6721-0358
Kimberly J PayneDepartment of Pathology and Human Anatomy, Loma Linda University, Loma Linda, CA 92350, USA.ORCID 0000-0002-7025-5821
Lori MufflyDivision of Blood and Marrow Transplantation, Stanford University, Stanford, CA 94305, USA.

Funding

Targeting CRLF2 and Ikaros Alterations to Reduce Health Disparities in Childhood LeukemiaR01CA209829 · NCI · LOMA LINDA UNIVERSITY · PI DOVAT, SINISA, DUERKSEN-HUGHES, PENELOPE J · 2016 to 2020
$2.0M
NCI NIH HHS R01 CA209829NCI NIH HHS R01CA209829
6 · The paper itself

Abstract

Philadelphia (Ph)-like acute lymphoblastic leukemia (ALL) is a high-risk B-cell Acute Lymphoblastic Leukemia (B-ALL) characterized by a gene expression profile similar to Ph-positive B-ALL but lacking the

Indexed as

TranscriptomeAnimalsFusion Proteins, bcr-ablGene Expression Regulation, LeukemicGenomicsHumansIkaros Transcription FactorPAX5 Transcription FactorPrecursor B-Cell Lymphoblastic Leukemia-LymphomaPrecursor Cell Lymphoblastic Leukemia-LymphomaReceptors, CytokineCRLF2 protein, humanFusion Proteins, bcr-ablIkaros Transcription FactorPAX5 protein, humanPAX5 Transcription FactorReceptors, Cytokineacute lymphoblastic leukemiaCRLF2PI3K/AKT/mTORtargeted therapy

Identifiers

PMID32235787
PMCPMC7139642

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.