Evidence map›Paper›PMID 32241392›Full record

ReviewAdvances in cancer research2020

Pubertal mammary development as a "susceptibility window" for breast cancer disparity.

Bradley Krisanits, Jaime F Randise, Clare E Burton, Victoria J Findlay, David P Turner

Open access · greenAbstract readReview
In one paragraph

Review in Advances in cancer research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
5.3field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 34 citations in OpenAlex.

  1. Review
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  6. International journal of molecular sciences · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Bradley KrisanitsDepartment of Pathology & Laboratory Medicine, Hollings Cancer Center, Medical University of South Carolina, Charleston, SC, United States.
Jaime F RandiseDepartment of Pathology & Laboratory Medicine, Hollings Cancer Center, Medical University of South Carolina, Charleston, SC, United States.
Clare E BurtonDepartment of Pathology & Laboratory Medicine, Hollings Cancer Center, Medical University of South Carolina, Charleston, SC, United States.
Victoria J FindlayDepartment of Pathology & Laboratory Medicine, Hollings Cancer Center, Medical University of South Carolina, Charleston, SC, United States.
David P TurnerDepartment of Pathology & Laboratory Medicine, Hollings Cancer Center, Medical University of South Carolina, Charleston, SC, United States. Electronic address: turnerda@musc.edu.
MUSC Hollings Cancer Center · USMedical University of South Carolina · US

Funding

South Carolina Cancer Disparities Research Center (SC CaDRe)U54CA210963 · NCI · SOUTH CAROLINA STATE UNIVERSITY · PI MCCRARY-QUARLES, AUDREY · 2017 to 2023
$6.1M
Lifestyle associated reactive metabolites and their negative impact on breast cancer riskR01CA245143 · NCI · VIRGINIA COMMONWEALTH UNIVERSITY · PI FINDLAY, VICTORIA JANE, TURNER, DAVID PAUL · 2020 to 2024
$2.1M
NCI NIH HHS R01 CA245143NCI NIH HHS U54 CA210963
6 · The paper itself

Abstract

Factors such as socioeconomic status, age at menarche and childbearing patterns are components that have been shown to influence mammary gland development and establish breast cancer disparity. Pubertal mammary gland development is selected as the focus of this review, as it is identified as a "window of susceptibility" for breast cancer risk and disparity. Here we recognize non-Hispanic White, African American, and Asian American women as the focus of breast cancer disparity, in conjunction with diets associated with changes in breast cancer risk. Diets consisting of high fat, N-3 polyunsaturated fatty acids, N-6 polyunsaturated fatty acids, as well as obesity and the Western diet have shown to lead to changes in pubertal mammary gland development in mammalian models, therefore increasing the risk of breast cancer and breast cancer disparity. While limited intervention strategies are offered to adolescents to mitigate development changes and breast cancer risk, the prominent solution to closing the disparity among the selected population is to foster lifestyle changes that avoid the deleterious effects of unhealthy diets.

Indexed as

Disease SusceptibilityBreastBreast NeoplasmsCell Transformation, NeoplasticDietFemaleHealthcare DisparitiesHumansBreast cancer disparityBreast cancer riskHealth interventionPubertal mammary gland development

Identifiers

PMID32241392
PMCPMC10084741
OpenAlexW3011048477

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.