Evidence map›Paper›PMID 32257924›Full record

ArticleToxicological research2020

Myristoylated TMEM39AS41, a cell-permeable peptide, causes lung cancer cell death.

Sungjin Park, Minhee Kim, Youngeun Hong, Hyunji Lee, Quangdon Tran, Chaeyeong Kim, So Hee Kwon, Jisoo Park, Jongsun Park, Seon-Hwan Kim

Open access · greenAbstract read
In one paragraph

Article in Toxicological research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.8field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 26 citations in OpenAlex.

  1. Biological Activity of Natural and Synthetic Peptides as Anticancer Agents.International journal of molecular sciences · 2024
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  9. Spermidine Attenuates Oxidative Stress-Induced Apoptosis via Blocking CaInternational journal of molecular sciences · 2021
    Article
  10. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Sungjin Park *1Department of Pharmacology, College of Medicine, Chungnam National University, Daejeon, 35015 Korea.
Minhee Kim *1Department of Pharmacology, College of Medicine, Chungnam National University, Daejeon, 35015 Korea.
Youngeun Hong *1Department of Pharmacology, College of Medicine, Chungnam National University, Daejeon, 35015 Korea.
Hyunji Lee1Department of Pharmacology, College of Medicine, Chungnam National University, Daejeon, 35015 Korea.
Quangdon Tran1Department of Pharmacology, College of Medicine, Chungnam National University, Daejeon, 35015 Korea.
Chaeyeong Kim1Department of Pharmacology, College of Medicine, Chungnam National University, Daejeon, 35015 Korea.
So Hee Kwon3College of Pharmacy, Yonsei Institute of Pharmaceutical Sciences, Yonsei University, Incheon, 21983 Korea.
Jisoo Park1Department of Pharmacology, College of Medicine, Chungnam National University, Daejeon, 35015 Korea.
Jongsun Park1Department of Pharmacology, College of Medicine, Chungnam National University, Daejeon, 35015 Korea.ORCID 0000-0002-4690-1854
Seon-Hwan Kim5Department of Neurosurgery, Institute for Cancer Research, College of Medicine, Chungnam National University, Daejeon, 35015 Korea.
Chungnam National University · KRDaejeon University · KRYonsei University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Lung cancer is the most common cause of cancer-associated death worldwide. Most patients with non-small cell lung cancer die within several years of the initial diagnosis, and new therapies are desperately needed. Transmembrane protein (TMEM) 39AS41, a synthetic peptide, was generated from the protein kinase B substrate motif

Indexed as

Cell-penetrating peptideLung cancerMyristic acidPeptide drugTMEM39A

Identifiers

PMID32257924
PMCPMC7099121
OpenAlexW3004439102

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.