Evidence mapPaperPMID 32257974Full record

ArticleProstate international2020

Relationship between body composition and hormone sensitivity for androgen deprivation therapy in patients with metastatic prostate cancer.

Eiji Kashiwagi, Masaki Shiota, Hiroyuki Masaoka, Kenjiro Imada, Keisuke Monji, Ario Takeuchi, Junichi Inokuchi, Katsunori Tatsugami, Masatoshi Eto

Abstract read
In one paragraph

Article in Prostate international, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Eiji KashiwagiDepartment of Urology, Graduate School of Medical Sciences, Kyushu University, Japan.
Masaki ShiotaDepartment of Urology, Graduate School of Medical Sciences, Kyushu University, Japan.
Hiroyuki MasaokaDepartment of Urology, Graduate School of Medical Sciences, Kyushu University, Japan.
Kenjiro ImadaDepartment of Urology, Graduate School of Medical Sciences, Kyushu University, Japan.
Keisuke MonjiDepartment of Urology, Graduate School of Medical Sciences, Kyushu University, Japan.
Ario TakeuchiDepartment of Urology, Graduate School of Medical Sciences, Kyushu University, Japan.
Junichi InokuchiDepartment of Urology, Graduate School of Medical Sciences, Kyushu University, Japan.
Katsunori TatsugamiDepartment of Urology, Graduate School of Medical Sciences, Kyushu University, Japan.
Masatoshi EtoDepartment of Urology, Graduate School of Medical Sciences, Kyushu University, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTo evaluate the relationship between body composition and the oncological outcome of androgen deprivation therapy (ADT), we investigated whether body composition features including the psoas muscle may be predictive factors of ADT.

methodsThis study enrolled patients with hormone-naïve metastatic prostate cancer who were treated with primary ADT from April 1996 to November 2013 at Kyushu University Hospital and who underwent a computed tomography scan before primary ADT for calculating body fat percentage, psoas muscle ratio (psoas muscle, cm

resultsOf the 178 patients enrolled, 60 patients died during follow-up. Median follow-up was 32 months, and progression-free survival and overall survival (OS) were 28 and 80 months, respectively. Multivariate analysis revealed that the psoas muscle ratio was correlated with OS (hazard ratio: 0.448; 95% confidence interval = 0.206-0.922;

conclusionsThis study demonstrated that higher psoas muscle ratio predicts longer OS among patients with nonlocalized prostate cancer treated with primary ADT.

Indexed as

Androgen deprivation therapyBody compositionProstate cancerPsoas muscleTestosterone

Identifiers

PMID32257974
PMCPMC7125377

What Socratic holds

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.