Evidence map›Paper›PMID 32273286›Full record

ArticleG3 (Bethesda, Md.)2020

Elyse L Christensen, Alexandra Beasley, Jessica Radchuk, Zachery E Mielko, Elicia Preston, Sidney Stuckett, John I Murray, Martin L Hudson

Open access · goldAbstract read
In one paragraph

Article in G3 (Bethesda, Md.), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
0.7field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
  2. Regulation of motor neuron differentiation in thebioRxiv : the preprint server for biology · 2025
    Article
  3. Article
  4. Review
  5. Functional analysis of conservedbioRxiv : the preprint server for biology · 2024
    Article
  6. Article
  7. Transcriptional regulation of neuronal identity.The European journal of neuroscience · 2022
    Review
  8. Article
  9. Article
  10. The bHLH-PAS genemicroPublication biology · 2021
    Article
  11. G3 (Bethesda, Md.) · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Elyse L ChristensenDepartment of Molecular and Cellular Biology, Kennesaw State University, GA 30144.
Alexandra BeasleyDepartment of Molecular and Cellular Biology, Kennesaw State University, GA 30144.
Jessica RadchukDepartment of Molecular and Cellular Biology, Kennesaw State University, GA 30144.
Zachery E MielkoDepartment of Molecular and Cellular Biology, Kennesaw State University, GA 30144.
Elicia PrestonPerelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104.
Sidney StuckettDepartment of Molecular and Cellular Biology, Kennesaw State University, GA 30144.
John I MurrayPerelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104.
Martin L HudsonDepartment of Molecular and Cellular Biology, Kennesaw State University, GA 30144 mhudso28@kennesaw.edu.ORCID 0000-0002-2628-035X
Kennesaw State University · USUniversity of Pennsylvania · US

Funding

Understanding the mechanobiology of stem cells in a microengineered 3D cardiac tissue environment with cardiomyopathyP20GM103638 · NIGMS · UNIVERSITY OF KANSAS LAWRENCE · PI LUNTE, SUSAN M · 2012 to 2021
$22.1M
Enhancing and expanding the CGC Strain CollectionP40OD010440 · OD · UNIVERSITY OF MINNESOTA · PI Aric L Daul, Ann E. Rougvie · 2012 to 2026
$7.5M
Decoding lineage and fate specification in the C. elegans embryoR35GM127093 · NIGMS · UNIVERSITY OF PENNSYLVANIA · PI MURRAY, JOHN ISAAC · 2018 to 2022
$2.0M
Interneuron shape and sensory circuit robustnessR15NS100632 · NINDS · KENNESAW STATE UNIVERSITY · PI HUDSON, MARTIN LYN · 2016 to 2016
$379k
NIGMS NIH HHS P20 GM103638NIGMS NIH HHS R35 GM127093NIH HHS P40 OD010440NINDS NIH HHS R15 NS100632
6 · The paper itself

Abstract

Proper nervous system development is required for an organism's survival and function. Defects in neurogenesis have been linked to neurodevelopmental disorders such as schizophrenia and autism. Understanding the gene regulatory networks that orchestrate neural development, specifically cascades of proneural transcription factors, can better elucidate which genes are most important during early neurogenesis. Neurogenins are a family of deeply conserved factors shown to be both necessary and sufficient for the development of neural subtypes. However, the immediate downstream targets of neurogenin are not well characterized. The objective of this study was to further elucidate the role of

Indexed as

Caenorhabditis elegansCaenorhabditis elegans ProteinsAnimalsBasic Helix-Loop-Helix ProteinsGene Expression Regulation, DevelopmentalNervous SystemNeuronsTranscription FactorsBasic Helix-Loop-Helix ProteinsCaenorhabditis elegans ProteinsNGN-1 protein, C elegansTranscription Factorsbasic-helix-loop-helixcell fate specificationcomparative transcriptomeproneuralRNAseq

Identifiers

PMID32273286
PMCPMC7263688
OpenAlexW3015827894

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.