Evidence map›Paper›PMID 32274584›Full record

ReviewJournal of neural transmission (Vienna, Austria : 1996)2020

Recent advances in radiotracers targeting norepinephrine transporter: structural development and radiolabeling improvements.

Xinyu Chen, Takashi Kudo, Constantin Lapa, Andreas Buck, Takahiro Higuchi

Open access · hybridAbstract readReview
In one paragraph

Review in Journal of neural transmission (Vienna, Austria : 1996), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
1.5field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 31 citations in OpenAlex.

  1. Trial
  2. Trial
  3. Review
  4. Article
  5. PET imaging of cardiac sympathetic nervous system dysfunction using meta-[European journal of nuclear medicine and molecular imaging · 2026
    Article
  6. Positron Emission Tomography (PET) Neuroimaging of theThe Journal of neuroscience : the official journal of the Society for Neuroscience · 2025
    Article
  7. Review
  8. Article
  9. Article
  10. PET, SPECT, and MRI imaging for evaluation of Parkinson's disease.American journal of nuclear medicine and molecular imaging · 2024
    Review
  11. Review
  12. PET reporter systems for the brain.Trends in neurosciences · 2023
    Review
  13. Article
  14. Review
  15. Review
  16. Prediction of appropriate ICD therapy in patients with ischemic heart failure.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2022
    Article
  17. Article
  18. Review
  19. Review
  20. [EJNMMI research · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 5 institutions in 2 countries.

Xinyu ChenDepartment of Nuclear Medicine, University Hospital of Würzburg, Oberdürrbacher Str. 6, 97080, Würzburg, Germany. chen_x@ukw.de.ORCID 0000-0002-6165-1689
Takashi KudoDepartment of Radioisotope Medicine, Atomic Bomb Disease Institute, Nagasaki University, Nagasaki, Japan.ORCID 0000-0002-8484-9209
Constantin LapaDepartment of Nuclear Medicine, University Hospital of Würzburg, Oberdürrbacher Str. 6, 97080, Würzburg, Germany.ORCID 0000-0001-7536-2207
Andreas BuckDepartment of Nuclear Medicine, University Hospital of Würzburg, Oberdürrbacher Str. 6, 97080, Würzburg, Germany.ORCID 0000-0002-6447-0613
Takahiro HiguchiDepartment of Nuclear Medicine, University Hospital of Würzburg, Oberdürrbacher Str. 6, 97080, Würzburg, Germany. higuchi_t@ukw.com.ORCID 0000-0001-9711-7835
Nagasaki University · JPOkayama University · JPUniversitätsklinikum Würzburg · DEUniversity Hospital Augsburg · DEUniversity of Augsburg · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The norepinephrine transporter (NET) is a major target for the evaluation of the cardiac sympathetic nerve system in patients with heart failure and Parkinson's disease. It is also used in the therapeutic applications against certain types of neuroendocrine tumors, as exemplified by the clinically used

Indexed as

Norepinephrine Plasma Membrane Transport ProteinsPositron-Emission TomographyCarbon RadioisotopesHumansKineticsSympathetic Nervous SystemCarbon RadioisotopesNorepinephrine Plasma Membrane Transport ProteinsAntidepressantBenzylguanidineNorepinephrine transporterOrganic cation transporterPhenethylguanidine

Identifiers

PMID32274584
PMCPMC7223405
OpenAlexW3015411346

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.