Evidence mapPaperPMID 32278617Full record

GuidelineKidney international2020

Blood pressure and volume management in dialysis: conclusions from a Kidney Disease: Improving Global Outcomes (KDIGO) Controversies Conference.

Jennifer E Flythe, Tara I Chang, Martin P Gallagher, Elizabeth Lindley, Magdalena Madero, Pantelis A Sarafidis, Mark L Unruh, Angela Yee-Moon Wang, Daniel E Weiner, Michael Cheung and 4 more

4 registry-linked trialsOpen access · bronzeAbstract readPractice Guideline
In one paragraph

Guideline in Kidney international, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 4 registered trials, which are not on this map. Cited by 128 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
128citing papers in PubMed, 5 pooled it
18.4field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05735288 completednot on this mapstarted 2023, after this paper: background citation

Pilot-scale, Single-arm, Observational Study to Assess the Utility of a Machine Learning Algorithm in Assessing Fluid Status in Haemodialysis Patients

TypeobservationalSponsorRoyal College of Surgeons, IrelandRan2023 to 2023Enrolled24ConditionsVolume Overload, Dialysis
NCT07459348 nanot yet recruitingnot on this mapstarted 2026, after this paper: background citation

Can Changes in Dialysate Sodium Concentration Improve Blood Pressure and Endothelial Function in Patients Undergoing Chronic Hemodialysis?

TypeinterventionalSponsorGødstrup HospitalRan2026 to 2029Enrolled25ConditionsDialysis Dependent Chronic Kidney Disease, Dialysis Patients, Sodium Excess, High Blood PressureArmsLow-Sodium Dialysate (133 mmol/L), Standard-Sodium Dialysate (139 mmol/L)
NCT07753876 enrolling by invitationnot on this mapstarted 2025, after this paper: background citation

Evaluation of Cuffless Blood Pressure Monitoring in Hemodialysis (CURE-HD) Study

TypeobservationalSponsorGangnam Severance HospitalRan2025 to 2026Enrolled240ConditionsEnd-Stage Renal DiseaseArmsCART BP Pro
NCT07762859 nanot yet recruitingnot on this mapstarted 2026, after this paper: background citation

Wearable Ambulatory Versus Office Blood Pressure-Guided Hypertension Management in Hemodialysis Patients: A Multicenter, Single-Blind, Randomized Controlled Trial

TypeinterventionalSponsorGangnam Severance HospitalRan2026 to 2027Enrolled280ConditionsESRD on HDArmsCART BP Pro-guided blood pressure management, Conventional office blood pressure-guided management
3 · Its place in the literature

Who cites it

128 citing papers in PubMed, 5 syntheses or guidelines pooled it, 245 citations in OpenAlex.

  1. Pooled it
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  11. A Narrative Summary of Strategies to Mitigate Intradialytic Hypotension in Poisoned Patients Requiring Extracorporeal Toxin Elimination.Journal of medical toxicology : official journal of the American College of Medical Toxicology · 2026
    Review
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68 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 15 institutions in 12 countries.

Jennifer E FlytheUniversity of North Carolina Kidney Center, Division of Nephrology and Hypertension, Department of Medicine, UNC School of Medicine, Chapel Hill, North Carolina, USA; Cecil G. Sheps Center for Health Services Research, University of North Carolina, Chapel Hill, North Carolina, USA. Electronic address: jflythe@med.unc.edu.
Tara I ChangDivision of Nephrology, Stanford University School of Medicine, Palo Alto, California, USA.
Martin P GallagherGeorge Institute for Global Health, Renal and Metabolic Division, Camperdown, Australia; Concord Repatriation General Hospital, Department of Renal Medicine, Sydney, Australia.
Elizabeth LindleyDepartment of Renal Medicine, Leeds Teaching Hospitals NHS Trust, Leeds, UK.
Magdalena MaderoDepartment of Medicine, Division of Nephrology, National Institute of Cardiology "Ignacio Chávez", Mexico City, Mexico.
Pantelis A SarafidisDepartment of Nephrology, Hippokration Hospital, Aristotle University of Thessaloniki, Thessaloniki, Greece.
Mark L UnruhDepartment of Internal Medicine, University of New Mexico School of Medicine, Albuquerque, New Mexico, USA.
Angela Yee-Moon WangDepartment of Medicine, Queen Mary Hospital, University of Hong Kong, Hong Kong, China.
Daniel E WeinerWilliam B. Schwartz Division of Nephrology, Tufts Medical Center, Boston, Massachusetts, USA.
Michael CheungKDIGO, Brussels, Belgium.
Michel JadoulDepartment of Nephrology, Cliniques universitaires Saint-Luc, Université catholique de Louvain, Brussels, Belgium.
Wolfgang C WinkelmayerSelzman Institute for Kidney Health, Section of Nephrology, Department of Medicine, Baylor College of Medicine, Houston, Texas, USA.
Kevan R PolkinghorneDepartment of Nephrology, Monash Health, Clayton, Melbourne, Australia; Department of Medicine, Monash University, Clayton, Melbourne, Australia; Department of Epidemiology and Preventive Medicine, Monash University, Prahan, Melbourne, Australia. Electronic address: kevan.polkinghorne@monash.edu.
Conference Participants
Baylor College of Medicine · USConcord Repatriation General Hospital · AUTufts Medical Center · USAristotle University of Thessaloniki · GRCentre d'Investigation Clinique Pierre Drouin · FRCliniques Universitaires Saint-Luc · BEInstituto Nacional de Cardiologia · BRLeeds Teaching Hospitals NHS Trust · GBMonash Health · AUQueen Mary Hospital · CNStanford Medicine · USUniversity of Delhi · INUniversity of New Mexico · USUniversity of North Carolina at Chapel Hill · USYork University · CA

Funding

NIDDK NIH HHS K23 DK109401NIDDK NIH HHS UH3 DK102384
6 · The paper itself

Abstract

Blood pressure (BP) and volume control are critical components of dialysis care and have substantial impacts on patient symptoms, quality of life, and cardiovascular complications. Yet, developing consensus best practices for BP and volume control have been challenging, given the absence of objective measures of extracellular volume status and the lack of high-quality evidence for many therapeutic interventions. In February of 2019, Kidney Disease: Improving Global Outcomes (KDIGO) held a Controversies Conference titled Blood Pressure and Volume Management in Dialysis to assess the current state of knowledge related to BP and volume management and identify opportunities to improve clinical and patient-reported outcomes among individuals receiving maintenance dialysis. Four major topics were addressed: BP measurement, BP targets, and pharmacologic management of suboptimal BP; dialysis prescriptions as they relate to BP and volume; extracellular volume assessment and management with a focus on technology-based solutions; and volume-related patient symptoms and experiences. The overarching theme resulting from presentations and discussions was that managing BP and volume in dialysis involves weighing multiple clinical factors and risk considerations as well as patient lifestyle and preferences, all within a narrow therapeutic window for avoiding acute or chronic volume-related complications. Striking this challenging balance requires individualizing the dialysis prescription by incorporating comorbid health conditions, treatment hemodynamic patterns, clinical judgment, and patient preferences into decision-making, all within local resource constraints.

Indexed as

Kidney DiseasesKidney Failure, ChronicBlood PressureBlood Pressure DeterminationHumansQuality of LifeRenal Dialysishemodialysispatient-reported outcome measuresperitoneal dialysisquality of liferesidual kidney function

Identifiers

PMID32278617
PMCPMC7215236
OpenAlexW3009144783

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.