Evidence map›Paper›PMID 32280540›Full record

ArticleInternational journal of hypertension2020

High-Serum Angiopoietin-Like Protein 3 Levels Associated with Cardiovascular Outcome in Patients with Coronary Artery Disease.

Ming-Chun Chen, Bang-Gee Hsu, Chung-Jen Lee, Ji-Hung Wang

Open access · goldAbstract read
In one paragraph

Article in International journal of hypertension, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.3field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 17 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Ming-Chun ChenDepartment of Pediatrics, Hualien Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, Hualien, Taiwan.ORCID https://orcid.org/0000-0003-0910-1185
Bang-Gee HsuSchool of Medicine, Tzu Chi University, Hualien, Taiwan.ORCID https://orcid.org/0000-0001-9364-4558
Chung-Jen LeeDepartment of Nursing, Tzu Chi University of Science and Technology, Hualien, Taiwan.ORCID https://orcid.org/0000-0003-1418-224X
Ji-Hung WangSchool of Medicine, Tzu Chi University, Hualien, Taiwan.ORCID https://orcid.org/0000-0002-0564-1726
Tzu Chi University · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAngiopoietin-like protein 3 (ANGPTL3) plays a pivotal role in lipid metabolism and angiogenesis, and there is growing interest regarding the association between ANGPTL3 and coronary artery disease (CAD). This study aims to investigate whether ANGPTL3 levels can be used to predict the future occurrence of major adverse cardiovascular events (MACEs) in patients with CAD.

methodsOverall, 90 patients with CAD were enrolled between January and December 2012. The study's primary endpoint was incidence of MACEs. Patient follow-up was completed on June 30, 2017.

resultsFollowing a median follow-up period of 54 months, 33 MACEs had occurred. Patients reporting MACEs had lower statin use (

conclusionsSerum ANGPTL3 levels could serve as a biomarker for future occurrence of MACEs in patients with CAD.

Identifiers

PMID32280540
PMCPMC7140125
OpenAlexW3013958772

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.