SynthesisNutrition journal2020
Effects of resistant starch interventions on circulating inflammatory biomarkers: a systematic review and meta-analysis of randomized controlled trials.
Synthesis in Nutrition journal, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 4 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
29 citing papers in PubMed, 4 syntheses or guidelines pooled it, 49 citations in OpenAlex.
- Effects of resistant starch consumption on anthropometric and serum parameters in adults with metabolic syndrome-related risks: a systematic review and meta-analysis.Frontiers in nutrition · 2025Pooled it
- Influencing factors of stroke in patients with type 2 diabetes: A systematic review and meta-analysis.PloS one · 2024Pooled it
- Associations between dietary fiber intake and cardiovascular risk factors: An umbrella review of meta-analyses of randomized controlled trials.Frontiers in nutrition · 2022Pooled it
- Inflammatory Markers in Cerebrospinal Fluid from Patients with Hydrocephalus: A Systematic Literature Review.Disease markers · 2021Pooled it
- Trial
- A randomized clinical trial investigating the impact of magnesium supplementation on clinical and biochemical measures in COVID-19 patients.Virology journal · 2024Trial
- Resistant starch as a dietary strategy for metabolic and gut health: Implications for Asia-Pacific populations.Asia Pacific journal of clinical nutrition · 2026Review
- Resistant Starch and Microbiota-Derived Secondary Metabolites: A Focus on Postbiotic Pathways in Gut Health and Irritable Bowel Syndrome.International journal of molecular sciences · 2025Review
- Association between dietary quality index-international (DQI-I) and cardiovascular diseases: insights from RaNCD cohort study.BMC nutrition · 2025Article
- The Nutritional Significance ofFood science & nutrition · 2025Review
- Dietary inflammation and its impact on congestive heart failure in older adults with depression.Scientific reports · 2025Article
- Comparison of the Structure, Physicochemical Properties, and Impact on Intestinal Flora of Processed and UnprocessedFoods (Basel, Switzerland) · 2025Article
- Obesity, composite dietary antioxidant index, and their interactive association with the risk of cardiometabolic multimorbidity in the elderly from a large national survey.Lipids in health and disease · 2025Article
- Impact of Dietary Fiber on Inflammation in Humans.International journal of molecular sciences · 2025Review
- The association between the dietary behavior, diet quality, and lifestyle scores with anthropometric indices and happiness levels among university students.BMC nutrition · 2024Article
- Association between Dietary total antioxidant capacity and knee osteoarthritis: a case-control study in the Iranian Population.BMC musculoskeletal disorders · 2024Article
- Dichotomous effect of dietary fiber in pediatrics: a narrative review of the health benefits and tolerance of fiber.European journal of clinical nutrition · 2024Review
- Association between dietary total antioxidant capacity and the risk of stroke: a nested case-control study.BMC nutrition · 2024Article
- Association of maternal exposure to endocrine disruptor chemicals with cardio-metabolic risk factors in children during childhood: a systematic review and meta-analysis of cohort studies.Diabetology & metabolic syndrome · 2024Review
- Bioactive Compounds from Pigmented Corn (Biomolecules · 2024Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeThis study aimed to summarize earlier studies on the effects of RS consumption on the serum levels of inflammatory biomarkers.
methodsA comprehensive search was done in the electronic databases that published from 1988 up to May 2019. Two reviewers independently performed screening, data extraction, and risk-of-bias assessment. We used from the effect size, as estimated by the mean difference to perform the fixed method meta-analysis.
resultsOverall, 13 studies with 14 effect sizes met the inclusion criteria and were included in the final analysis. Sample size of these studies ranged from 15 to 75 and intervention duration ranged from 4 to 14 weeks. Meta-analysis revealed that higher consumption of resistant starch caused a significant reduction in the interleukin 6 (weighted mean difference = - 1.11 pg/mL; 95% CI: - 1.72, - 0.5 pg/mL; P = < 0.001) and tumor necrosis factor alpha (weighted mean difference = - 2.19 pg/mL; 95% CI: - 3.49, - 0.9 pg/mL; P = 0.001) levels. However, no significant changes were found in C-reactive protein concentration (weighted mean difference = - 0.21 mg/L; 95% CI: - 1.06, 0.63 mg/L; P = 0.61). Moreover, the changes in interleukin 6 concentration was dependent on study quality and intervention duration.
conclusionThe current meta-analysis indicated that RS intake can improve some inflammatory biomarkers. More research, with a large sample sizes and accurate design is recommended.
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What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.