Evidence map›Paper›PMID 32295871›Full record

ArticlemSphere2020

The Diversity Outbred Mouse Population Is an Improved Animal Model of Vaccination against Tuberculosis That Reflects Heterogeneity of Protection.

Sherry L Kurtz, Amy P Rossi, Gillian L Beamer, Dan M Gatti, Igor Kramnik, Karen L Elkins

Open access · goldAbstract read
In one paragraph

Article in mSphere, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 50 papers.

0numbers the graph read from it
0cells of the map it votes in
50citing papers in PubMed
0.9field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

50 citing papers in PubMed, 61 citations in OpenAlex.

  1. Review
  2. Article
  3. HowVaccines · 2026
    Review
  4. Article
  5. Article
  6. Fifteen years of the Diversity Outbred mouse model: a review.Mammalian genome : official journal of the International Mammalian Genome Society · 2026
    Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Review
  13. Review
  14. Article
  15. Methods and Models for StudyingInternational journal of molecular sciences · 2024
    Review
  16. Review
  17. Article
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 5 institutions in 1 country.

Sherry L KurtzCenter for Biologics Evaluation and Research, Food and Drug Administration, Silver Spring, Maryland, USA sherry.kurtz@fda.hhs.gov karen.elkins@fda.hhs.gov.
Amy P RossiUniversity of Cincinnati College of Medicine, Cincinnati, Ohio, USA.
Gillian L BeamerCummings School of Veterinary Medicine, Tufts University, North Grafton, Massachusetts, USA.
Dan M GattiCollege of the Atlantic, Bar Harbor, Maine, USA.
Igor KramnikDepartment of Medicine, Boston University School of Medicine, Boston, Massachusetts, USA.
Karen L ElkinsCenter for Biologics Evaluation and Research, Food and Drug Administration, Silver Spring, Maryland, USA sherry.kurtz@fda.hhs.gov karen.elkins@fda.hhs.gov.
Center for Biologics Evaluation and Research · USBoston University · USCollege of the Atlantic · USTufts University · USUniversity of Cincinnati Medical Center · US

Funding

Medical Scientist Training ProgramT32GM063483 · NIGMS · UNIVERSITY OF CINCINNATI · PI KHURANA HERSHEY, GURJIT K. · 2002 to 2022
$6.7M
Necrosis in pulmonary TB granulomas: dynamics, mechanisms, therapiesR01HL126066 · NHLBI · BOSTON UNIVERSITY MEDICAL CAMPUS · PI KRAMNIK, IGOR, NIEDERWEIS, MICHAEL · 2016 to 2025
$5.6M
Predicting tuberculosis outcomes using genotypic and biomarker signaturesR01HL145411 · NHLBI · TUFTS UNIVERSITY BOSTON · PI BEAMER, GILLIAN L · 2019 to 2023
$3.4M
Aberrant immune activation in the tuberculosis granuloma: a pivotal role in necrosisR01HL133190 · NHLBI · BOSTON UNIVERSITY MEDICAL CAMPUS · PI BISHAI, WILLIAM RAMSES, KRAMNIK, IGOR · 2016 to 2019
$3.0M
NHLBI NIH HHS R01 HL126066NHLBI NIH HHS R01 HL133190NHLBI NIH HHS R01 HL145411NIGMS NIH HHS T32 GM063483
6 · The paper itself

Abstract

Many studies of

Indexed as

Disease Models, AnimalAnimalsCollaborative Cross MiceFemaleGenetic VariationMaleMiceMice, Inbred C57BLMycobacterium tuberculosisTuberculosisTuberculosis VaccinesVaccinationTuberculosis Vaccinesanimal modelsDiversity OutbredimmunizationMycobacterium tuberculosistuberculosis vaccinesvaccines

Identifiers

PMID32295871
PMCPMC7160682
OpenAlexW3017335882

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.