Evidence map›Paper›PMID 32300244›Full record

ArticleActa pharmacologica Sinica2020

Exogenous pancreatic kininogenase protects against renal fibrosis in rat model of unilateral ureteral obstruction.

Ji-Zhe Jin, Hui-Ying Li, Jian Jin, Shang-Guo Piao, Xiong-Hu Shen, Yan-Ling Wu, Jia-Chong Xu, Long-Ye Zhang, Yu-Ji Jiang, Hai-Lan Zheng and 5 more

Open access · bronzeAbstract read
In one paragraph

Article in Acta pharmacologica Sinica, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
1.5field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 20 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 2 institutions in 1 country.

Ji-Zhe JinDepartment of Nephrology, Yanbian University Hospital, Yanji, 133000, China.
Hui-Ying LiDepartment of Nephrology, Yanbian University Hospital, Yanji, 133000, China.
Jian JinDepartment of Nephrology, Yanbian University Hospital, Yanji, 133000, China.
Shang-Guo PiaoDepartment of Nephrology, Yanbian University Hospital, Yanji, 133000, China.
Xiong-Hu ShenDepartment of Oncology, Yanbian University Hospital, Yanji, 133000, China.
Yan-Ling WuDepartment of Pharmacology, Yanbian University, Yanji, 133000, China.
Jia-Chong XuAnimal Care Institute, Yanbian University, Yanji, 133000, China.
Long-Ye ZhangDepartment of Nephrology, Yanbian University Hospital, Yanji, 133000, China.
Yu-Ji JiangDepartment of Nephrology, Yanbian University Hospital, Yanji, 133000, China.
Hai-Lan ZhengDepartment of Nephrology, Yanbian University Hospital, Yanji, 133000, China.
Ying-Shun JinDepartment of Nephrology, Yanbian University Hospital, Yanji, 133000, China.
Sheng CuiDepartment of Nephrology, Yanbian University Hospital, Yanji, 133000, China.
Kang LuoDepartment of Nephrology, Yanbian University Hospital, Yanji, 133000, China.
Yi QuanDepartment of Nephrology, Yanbian University Hospital, Yanji, 133000, China.
Can LiDepartment of Nephrology, Yanbian University Hospital, Yanji, 133000, China. lican@ybu.edu.cn.
Yanbian University Hospital · CNYanbian University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Tissue kallikrein has protective function against various types of injury. In this study, we investigated whether exogenous pancreatic kininogenase (PK) conferred renoprotection in a rat model of unilateral ureteral obstruction (UUO) and H

Indexed as

AnimalsCell DeathCell LineFibrosisHumansInflammationKallikrein-Kinin SystemKallikreinsKidneyMaleOxidative StressPancreasProtective AgentsRats, Sprague-DawleySignal TransductionUreteral ObstructionKallikreinsProtective Agentsapoptosisautophagykallikreinoxidative stressrenal fibrosis

Identifiers

PMID32300244
PMCPMC7921586
OpenAlexW3016941684

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.