Evidence map›Paper›PMID 32300901›Full record

SynthesisHernia : the journal of hernias and abdominal wall surgery2020

The emerging role of sarcopenia as a prognostic indicator in patients undergoing abdominal wall hernia repairs: a systematic review of the literature.

S T Clark, G Malietzis, T N Grove, J T Jenkins, A C J Windsor, C Kontovounisios, O J Warren

Open access · hybridAbstract readSystematic Review
In one paragraph

Synthesis in Hernia : the journal of hernias and abdominal wall surgery, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 1 pooled it
2.4field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 1 synthesis or guideline pooled it, 34 citations in OpenAlex.

  1. Pooled it
  2. Review
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  15. "Sarcopenia is associated with increased risk of burst abdomen after emergency midline laparotomy: a matched case-control study".European journal of trauma and emergency surgery : official publication of the European Trauma Society · 2022
    Article
  16. Geriatric assessment and medical preoperative screening (GrAMPS) program for older hernia patients.Hernia : the journal of hernias and abdominal wall surgery · 2022
    Article
  17. Abdominal wall hernia is a frequent complication of polycystic liver disease and associated with hepatomegaly.Liver international : official journal of the International Association for the Study of the Liver · 2022
    Article
  18. Review
  19. Sarcopenia: Etiology, Nutritional Approaches, and miRNAs.International journal of molecular sciences · 2021
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 2 countries.

S T ClarkFaculty of Medical and Health Sciences, University of Auckland, Grafton, Auckland, New Zealand.
G MalietzisColorectal Surgical Unit, Chelsea and Westminster Hospital, Chelsea, London, UK.
T N GroveColorectal Surgical Unit, Chelsea and Westminster Hospital, Chelsea, London, UK.
J T JenkinsDepartment of Surgery, St. Mark's Hospital, Watford Road, Harrow, Middlesex, UK.
A C J WindsorHCA Healthcare, London, UK.
C KontovounisiosColorectal Surgical Unit, Chelsea and Westminster Hospital, Chelsea, London, UK. c.kontovounisios@imperial.ac.uk.
O J WarrenDepartment of Surgery and Cancer, Imperial College, Chelsea and Westminster and the Royal Marsden Campus, Paddington, London, UK.
Chelsea and Westminster Hospital · GBInforma Healthcare · GBSt Mark's Hospital · GBUniversity of Auckland · NZ

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThere is strong evidence suggesting that excessive fat distribution, for example, in the bowel mesentery or a reduction in lean body mass (sarcopenia) can influence short-, mid-, and long-term outcomes from patients undergoing various types of surgery. Body composition (BC) analysis aims to measure and quantify this into a parameter that can be used to assess patients being treated for abdominal wall hernia (AWH). This study aims to review the evidence linking quantification of BC with short- and long-term abdominal wall hernia repair outcomes.

methodsA systematic review was performed according to the PRISMA guidelines. The literature search was performed on all studies that included BC analysis in patients undergoing treatment for AWH using Medline, Google Scholar and Cochrane databases by two independent reviewers. Outcomes of interest included short-term recovery, recurrence outcomes, and long-term data.

results201 studies were identified, of which 4 met the inclusion criteria. None of the studies were randomized controlled trials and all were cohort studies. There was considerable variability in the landmark axial levels and skeletal muscle(s) chosen for analysis, alongside the methods of measuring the cross-sectional area and the parameters used to define sarcopenia. Only two studies identified an increased risk of postoperative complications associated with the presence of sarcopenia. This included an increased risk of hernia recurrence, postoperative ileus and prolonged hospitalisation.

conclusionThere is some evidence to suggest that BC techniques could be used to help predict surgical outcomes and allow early optimisation in AWH patients. However, the lack of consistency in chosen methodology, combined with the outdated definitions of sarcopenia, makes drawing any conclusions difficult. Whether body composition modification can be used to improve outcomes remains to be determined.

Indexed as

Abdominal WallDigestive System Surgical ProceduresFemaleHerniorrhaphyHumansMaleMiddle AgedPrognosisSarcopeniaAbdominal wall reconstructionBody compositionOutcomesSarcopeniaSystematic reviewVentral herniaVisceral obesity

Identifiers

PMID32300901
PMCPMC7701077
OpenAlexW3016315254

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.