Evidence map›Paper›PMID 32301059›Full record

ArticleMolecular and cellular biochemistry2020

Ticagrelor reverses the mitochondrial dysfunction through preventing accumulated autophagosomes-dependent apoptosis and ER stress in insulin-resistant H9c2 myocytes.

Yusuf Olgar, Erkan Tuncay, Deniz Billur, Aysegul Durak, Semir Ozdemir, Belma Turan

Abstract read
PubMed Publisher
In one paragraph

Article in Molecular and cellular biochemistry, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.2field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. Synthesis, characterization andNanoscale advances · 2025
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  4. Review
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  6. Review
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  8. Article
  9. The role of labile ZnMolecular and cellular biochemistry · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Yusuf OlgarDepartments of Biophysics, Faculty of Medicine, Ankara University, Ankara, Turkey.
Erkan TuncayDepartments of Biophysics, Faculty of Medicine, Ankara University, Ankara, Turkey.
Deniz BillurDepartments of Histology-Embryology, Faculty of Medicine, Ankara University, Ankara, Turkey.
Aysegul DurakDepartments of Biophysics, Faculty of Medicine, Ankara University, Ankara, Turkey.
Semir OzdemirDepartments of Biophysics, Faculty of Medicine, Akdeniz University, Antalya, Turkey. osemir@akdeniz.edu.tr.
Belma TuranDepartments of Biophysics, Faculty of Medicine, Ankara University, Ankara, Turkey. belma.turan@medicine.ankara.edu.tr.ORCID http://orcid.org/0000-0003-2583-9294
Ankara University · TRAkdeniz University · TR

Funding

TUBITAK SBAG-216S979
6 · The paper itself

Abstract

Ticagrelor, a P

Indexed as

AnimalsApoptosisAutophagosomesBeclin-1CalciumCell LineEndoplasmic Reticulum StressEquilibrative Nucleoside Transporter 1InsulinMembrane Potential, MitochondrialMicroscopy, ElectronMitochondriaMyocytes, CardiacPalmitic AcidRatsReactive Oxygen SpeciesBeclin-1Becn1 protein, ratCalciumEquilibrative Nucleoside Transporter 1InsulinP2ry12 protein, ratPalmitic AcidReactive Oxygen SpeciesReceptors, Purinergic P2Y12Slc29a1 protein, ratTicagrelorATPHeart functionInsulin resistanceMitochondriaP2Y12 receptorsROS

Identifiers

PMID32301059
OpenAlexW3017106602

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.