ArticleeLife2020
A complex regulatory landscape involved in the development of mammalian external genitals.
Article in eLife, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed, 34 citations in OpenAlex.
- Article
- Article
- Multimodal Hox5 activity generates motor neuron diversity.Communications biology · 2024Article
- Pre-hypertrophic chondrogenic enhancer landscape of limb and axial skeleton development.Nature communications · 2024Article
- 3D genome alterations and editing in pathology.Molecular therapy : the journal of the American Society of Gene Therapy · 2023Review
- Context-dependent enhancer function revealed by targeted inter-TAD relocation.Nature communications · 2022Article
- Developmental and evolutionary comparative analysis of a regulatory landscape in mouse and chicken.Development (Cambridge, England) · 2022Article
- 3D chromatin architecture and transcription regulation in cancer.Journal of hematology & oncology · 2022Review
- Inversion of a topological domain leads to restricted changes in its gene expression and affects interdomain communication.Development (Cambridge, England) · 2022Article
- Sequential inGenes & development · 2021Article
- Dbx2 regulation in limbs suggests interTAD sharing of enhancers.Developmental dynamics : an official publication of the American Association of Anatomists · 2021Article
- Mesomelic dysplasias associated with the HOXD locus are caused by regulatory reallocations.Nature communications · 2021Article
- Sexual fate of murine external genitalia development: Conserved transcriptional competency for male-biased genes in both sexes.Proceedings of the National Academy of Sciences of the United States of America · 2021Article
- Identification of in vivo Hox13-binding sites reveals an essential locus controlling zebrafish brachyury expression.Development (Cambridge, England) · 2021Article
- Chromatin topology and the timing of enhancer function at theProceedings of the National Academy of Sciences of the United States of America · 2020Article
- Differential abilities to engage inaccessible chromatin diversify vertebrate Hox binding patterns.Development (Cambridge, England) · 2020Article
- Single-gene imaging links genome topology, promoter-enhancer communication and transcription control.Nature structural & molecular biology · 2020Article
- A complex regulatory landscape involved in the development of mammalian external genitals.eLife · 2020Article
- The regulatory landscapes of developmental genes.Development (Cambridge, England) · 2020Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 2 institutions in 2 countries.
Funding
Abstract
Developmental genes are often controlled by large regulatory landscapes matching topologically associating domains (TADs). In various contexts, the associated chromatin backbone is modified by specific enhancer-enhancer and enhancer-promoter interactions. We used a TAD flanking the mouse
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.