Evidence map›Paper›PMID 32301741›Full record

ArticleJMIR medical informatics2020

Impact of a "Chart Closure" Hard Stop Alert on Prescribing for Elevated Blood Pressures Among Patients With Diabetes: Quasi-Experimental Study.

Magaly Ramirez, Kimberly Chen, Robert W Follett, Carol M Mangione, Gerardo Moreno, Douglas S Bell

Open access · goldAbstract read
In one paragraph

Article in JMIR medical informatics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
0.6field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it, 6 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Magaly RamirezDepartment of Health Services, School of Public Health, University of Washington, Seattle, WA, United States.ORCID https://orcid.org/0000-0001-5063-1028
Kimberly ChenClinical Informatics, UCLA Health, Los Angeles, CA, United States.ORCID https://orcid.org/0000-0002-2064-620X
Robert W FollettClinical Informatics, UCLA Health, Los Angeles, CA, United States.ORCID https://orcid.org/0000-0003-1618-2817
Carol M MangioneDivision of General Internal Medicine and Health Services Research, Department of Medicine, David Geffen School of Medicine, University of California at Los Angeles, Los Angeles, CA, United States.ORCID https://orcid.org/0000-0002-9475-2275
Gerardo MorenoDepartment of Family Medicine, David Geffen School of Medicine, University of California at Los Angeles, Los Angeles, CA, United States.ORCID https://orcid.org/0000-0002-3476-4274
Douglas S BellDivision of General Internal Medicine and Health Services Research, Department of Medicine, David Geffen School of Medicine, University of California at Los Angeles, Los Angeles, CA, United States.ORCID https://orcid.org/0000-0002-5063-8294
University of California, Los Angeles · USUCLA Health · USUniversity of Washington · US

Funding

UCLA Clinical Translational Science InstituteUL1TR001881 · NCATS · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI ARLEEN F. BROWN, ARASH NAEIM · 2016 to 2026
$118.1M
The Center for Health Improvement of Minority ElderlyP30AG021684 · NIA · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI CATHERINE A SARKISIAN · 2002 to 2026
$19.7M
UCLA/RAND HEALTH SERVICES RESEARCH TRAINING PROGRAMT32HS000046 · AHRQ · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI EISENBERG, DANIEL · 1992 to 2024
$8.7M
Health IT decision support to improve medication management safety and qualityK23AG042961 · NIA · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI MORENO, GERARDO · 2012 to 2016
$699k
AHRQ HHS T32 HS000046NCATS NIH HHS UL1 TR001881NIA NIH HHS K23 AG042961NIA NIH HHS P30 AG021684
6 · The paper itself

Abstract

backgroundUniversity of California at Los Angeles Health implemented a Best Practice Advisory (BPA) alert for the initiation of an angiotensin-converting enzyme inhibitor (ACEI) or angiotensin-receptor blocker (ARB) for individuals with diabetes. The BPA alert was configured with a "chart closure" hard stop, which demanded a response before closing the chart.

objectiveThe aim of the study was to evaluate whether the implementation of the BPA was associated with changes in ACEI and ARB prescribing during primary care encounters for patients with diabetes.

methodsWe defined ACEI and ARB prescribing opportunities as primary care encounters in which the patient had a diabetes diagnosis, elevated blood pressure in recent encounters, no active ACEI or ARB prescription, and no contraindications. We used a multivariate logistic regression model to compare the change in the probability of an ACEI or ARB prescription during opportunity encounters before and after BPA implementation in primary care sites that did (n=30) and did not (n=31) implement the BPA. In an additional subgroup analysis, we compared ACEI and ARB prescribing in BPA implementation sites that had also implemented a pharmacist-led medication management program.

resultsWe identified a total of 2438 opportunity encounters across 61 primary care sites. The predicted probability of an ACEI or ARB prescription increased significantly from 11.46% to 22.17% during opportunity encounters in BPA implementation sites after BPA implementation. However, in the subgroup analysis, we only observed a significant improvement in ACEI and ARB prescribing in BPA implementation sites that had also implemented the pharmacist-led program. Overall, the change in the predicted probability of an ACEI or ARB prescription from before to after BPA implementation was significantly greater in BPA implementation sites compared with nonimplementation sites (difference-in-differences of 11.82; P<.001).

conclusionsA BPA with a "chart closure" hard stop is a promising tool for the treatment of patients with comorbid diabetes and hypertension with an ACEI or ARB, especially when implemented within the context of team-based care, wherein clinical pharmacists support the work of primary care providers.

Indexed as

decision support systems, clinicaldiabetes mellitusdrug prescriptionshypertension

Identifiers

PMID32301741
PMCPMC7195665
OpenAlexW2992289061

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.