Evidence map›Paper›PMID 32306870›Full record

ReviewPhilosophical transactions of the Royal Society of London. Series B, Biological sciences2020

The specific biochemistry of human axilla odour formation viewed in an evolutionary context.

Andreas Natsch, Roger Emter

Open access · hybridAbstract readReview
In one paragraph

Review in Philosophical transactions of the Royal Society of London. Series B, Biological sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed, 2 pooled it
2.1field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed, 2 syntheses or guidelines pooled it, 57 citations in OpenAlex.

  1. Pooled it
  2. Major histocompatibility complex-associated odour preferences and human mate choice: near and far horizons.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2020
    Pooled it
  3. Article
  4. Article
  5. Article
  6. Article
  7. Human Body Malodor and Deodorants: The Present and the Future.International journal of molecular sciences · 2025
    Review
  8. Article
  9. Article
  10. Past, Present, and Future of Human Chemical Communication Research.Perspectives on psychological science : a journal of the Association for Psychological Science · 2025
    Review
  11. Article
  12. Article
  13. Review
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. No skin off your back: the sampling and extraction of sebum for metabolomics.Metabolomics : Official journal of the Metabolomic Society · 2023
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Andreas NatschGivaudan Schweiz AG, Kemptpark 50, CH-8310 Kemptthal, Switzerland.
Roger EmterGivaudan Schweiz AG, Kemptpark 50, CH-8310 Kemptthal, Switzerland.
Givaudan (Switzerland) · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Human body odour is dominated by the scent of specific odourants emanating from specialized glands in the axillary region. These specific odourants are produced by an intricate interplay between biochemical pathways in the host and odour-releasing enzymes present in commensal microorganisms of the axillary microbiome. Key biochemical steps for the release of highly odouriferous carboxylic acids and sulfur compounds have been elucidated over the past 15 years. Based on the profound molecular understanding and specific analytical methods developed, evolutionary questions could be asked for the first time with small population studies: (i) a genetic basis for body odour could be shown with a twin study, (ii) no effect of genes in the human leukocyte antigen complex on the pattern of odourant carboxylic acid was found, and (iii) loss of odour precursor secretion by a mutation in the

Indexed as

Biological EvolutionSmellAmidohydrolasesAxillaBacteriaBacterial ProteinsHumansOdorantsOlfactory PerceptionAmidohydrolasesaminoacylase IBacterial Proteinsaminoacylaseaxillahuman body odoursodour precursorsskin microbiome

Identifiers

PMID32306870
PMCPMC7209930
OpenAlexW3011447097

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.