Evidence map›Paper›PMID 32324478›Full record

ArticleJournal of applied physiology (Bethesda, Md. : 1985)2020

Passive leg movement in chronic obstructive pulmonary disease: evidence of locomotor muscle vascular dysfunction.

Stephen J Ives, Gwenael Layec, Corey R Hart, Joel D Trinity, Jayson R Gifford, Ryan S Garten, Melissa A H Witman, Jacob R Sorensen, Russell S Richardson

Open access · bronzeAbstract read
In one paragraph

Article in Journal of applied physiology (Bethesda, Md. : 1985), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.9field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. The role of the endothelium in the hyperemic response to passive leg movement: looking beyond nitric oxide.American journal of physiology. Heart and circulatory physiology · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 1 country.

Stephen J IvesGeriatric Research, Education, and Clinical Center, George E. Whalen Department of Veterans Affairs Medical Center, Salt Lake City, Utah.
Gwenael LayecGeriatric Research, Education, and Clinical Center, George E. Whalen Department of Veterans Affairs Medical Center, Salt Lake City, Utah.
Corey R HartGeriatric Research, Education, and Clinical Center, George E. Whalen Department of Veterans Affairs Medical Center, Salt Lake City, Utah.
Joel D TrinityGeriatric Research, Education, and Clinical Center, George E. Whalen Department of Veterans Affairs Medical Center, Salt Lake City, Utah.
Jayson R GiffordGeriatric Research, Education, and Clinical Center, George E. Whalen Department of Veterans Affairs Medical Center, Salt Lake City, Utah.
Ryan S GartenGeriatric Research, Education, and Clinical Center, George E. Whalen Department of Veterans Affairs Medical Center, Salt Lake City, Utah.
Melissa A H WitmanGeriatric Research, Education, and Clinical Center, George E. Whalen Department of Veterans Affairs Medical Center, Salt Lake City, Utah.
Jacob R SorensenDepartment of Exercise Sciences, Brigham Young University, Provo, Utah.ORCID 0000-0001-5945-542X
Russell S RichardsonGeriatric Research, Education, and Clinical Center, George E. Whalen Department of Veterans Affairs Medical Center, Salt Lake City, Utah.
University of Utah · USBrigham Young University · USSkidmore College · USVirginia Commonwealth University · US

Funding

Tissue Imaging, Biochemistry and MorphologyP01HL091830 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI WAGNER, PETER D · 2009 to 2013
$10.1M
Nitric oxide coupling and BH4 availability roles in muscle dysfunction with COPDR00HL125756 · NHLBI · UNIVERSITY OF MASSACHUSETTS AMHERST · PI LAYEC, GWENAEL · 2018 to 2020
$738k
Nitric oxide coupling and BH4 availability roles in muscle dysfunction with COPDK99HL125756 · NHLBI · UNIVERSITY OF UTAH · PI LAYEC, GWENAEL · 2015 to 2016
$300k
NHLBI NIH HHS K99 HL125756NHLBI NIH HHS P01 HL091830NHLBI NIH HHS R00 HL125756
6 · The paper itself

Abstract

Chronic obstructive pulmonary disease (COPD), characterized by pulmonary dysfunction, is now also recognized to be associated with free radical-mediated vascular dysfunction. However, as previous investigations have utilized the brachial artery flow-mediated dilation technique, whether such vascular dysfunction exists in the locomotor muscle of patients with COPD remains unclear. Therefore, in patients with COPD (

Indexed as

LegPulmonary Disease, Chronic ObstructiveHumansMovementMusclesMuscle, SkeletalRegional Blood FlowVasodilationCOPDendotheliumnitric oxidePLM

Identifiers

PMID32324478
PMCPMC7272759
OpenAlexW3020294324

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.