Evidence map›Paper›PMID 32327722›Full record

ArticleInternational journal of obesity (2005)2020

Predictors of weight loss after bariatric surgery-a cross-disciplinary approach combining physiological, social, and psychological measures.

Mette S Nielsen, Bodil Just Christensen, Julie Berg Schmidt, Louise Tækker, Lotte Holm, Susanne Lunn, Christian Ritz, Nicolai J Wewer Albrechtsen, Jens Juul Holst, Theresia M Schnurr and 5 more

Abstract read
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In one paragraph

Article in International journal of obesity (2005), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed.

  1. Trial
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  5. Relations between trajectories of weight loss and changes in psychological health over a period of 2 years following bariatric metabolic surgery.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2025
    Article
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  8. Sex- and operation-dependent effects on 5-year weight loss results of bariatric surgery.Surgery for obesity and related diseases : official journal of the American Society for Bariatric Surgery · 2024
    Observational
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Mette S Nielsen *Department of Nutrition, Exercise and Sports, Faculty of Science, University of Copenhagen, Copenhagen, Denmark.ORCID http://orcid.org/0000-0001-7354-4648
Bodil Just Christensen *Department of Food and Resource Economics, Faculty of Science , University of Copenhagen, Copenhagen, Denmark.
Julie Berg SchmidtDepartment of Nutrition, Exercise and Sports, Faculty of Science, University of Copenhagen, Copenhagen, Denmark.ORCID http://orcid.org/0000-0002-0299-7874
Louise TækkerDepartment of Psychology, Faculty of Social Science, University of Copenhagen, Copenhagen, Denmark.ORCID http://orcid.org/0000-0003-0363-6090
Lotte HolmDepartment of Food and Resource Economics, Faculty of Science , University of Copenhagen, Copenhagen, Denmark.ORCID http://orcid.org/0000-0003-0667-7779
Susanne LunnDepartment of Psychology, Faculty of Social Science, University of Copenhagen, Copenhagen, Denmark.ORCID http://orcid.org/0000-0002-6812-1867
Christian RitzDepartment of Nutrition, Exercise and Sports, Faculty of Science, University of Copenhagen, Copenhagen, Denmark.ORCID http://orcid.org/0000-0002-5095-0624
Nicolai J Wewer AlbrechtsenDepartment of Clinical Biochemistry, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark.ORCID http://orcid.org/0000-0003-4230-5753
Jens Juul HolstDepartment of Biomedical Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.ORCID http://orcid.org/0000-0001-6853-3805
Theresia M SchnurrNovo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.ORCID http://orcid.org/0000-0002-6573-4959
Torben HansenNovo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.ORCID http://orcid.org/0000-0001-8748-3831
Carel W le RouxInvestigative Science, Imperial College London, London, UK.ORCID http://orcid.org/0000-0001-5521-5445
Thomas Bøker LundDepartment of Food and Resource Economics, Faculty of Science , University of Copenhagen, Copenhagen, Denmark.ORCID http://orcid.org/0000-0001-5282-1562
Andrea Karen FloydBariatric Center, Hospital South West Jutland, University of Southern Denmark, Esbjerg, Denmark.
Anders SjödinDepartment of Nutrition, Exercise and Sports, Faculty of Science, University of Copenhagen, Copenhagen, Denmark. amsj@nexs.ku.dk.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundBariatric surgery leads to a substantial weight loss (WL), however, a subset of patients undergoing surgery fails to achieve adequate WL. The reason for the individual variation in WL remains unexplained. Using an exploratory cross-disciplinary approach, we aimed to identify preoperative and early postoperative factors explaining the variation in WL after bariatric surgery.

methodsSixty-one subjects were recruited. Eighteen subjects did not receive surgery and three subjects dropped out, leaving a total sample of 40 subjects. Physiological, social, and psychological data were collected before and 6 months after surgery. All variables were analyzed in combination using a least absolute shrinkage and selection operator (LASSO) regression to explain the variation in WL 18 months after Roux-en-Y gastric bypass (n = 30) and sleeve gastrectomy (n = 10).

resultsMean WL was 31% (range: 10-52%). The following preoperative factors predicted 59% of the variation in WL: type of surgery (14%), diabetes status (12%), economic resources (9%), sex (7%), binge eating disorder (7%), degree of depression (5%), household type (3%), and physical activity (1%). Including information on early responses after surgery increased the ability to predict WL to 78% and was explained by early WL (47%), changes in energy density of food consumed from a buffet meal (9%), changes in glicentin (5%), degree of depression (5%), sex (5%), type of surgery (2%), economic resources (2%), and changes in drive for thinness (1%).

conclusionsUsing a cross-disciplinary approach, a substantial part of the individual variation in WL was explained by a combination of basic patient characteristics, psychological profile, and social conditions as well as physiological, psychological and behavioral responses to surgery. These results suggest that patient characteristics collected in a cross-disciplinary approach may help determine predictors for less successful WL after bariatric surgery. If verified in larger cohorts this may form the basis for individualized postoperative support to optimize WL outcome.

Indexed as

Bariatric SurgeryWeight LossAdultDenmarkFemaleForecastingGastrectomyGastric BypassHumansMaleMental HealthMiddle AgedObesity, MorbidProspective StudiesSocioeconomic FactorsTreatment Outcome

Identifiers

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.