Evidence map›Paper›PMID 32344932›Full record

ArticleMolecules (Basel, Switzerland)2020

Trypanocidal Activity of Four Sesquiterpene Lactones Isolated from Asteraceae Species.

Orlando G Elso, Augusto E Bivona, Andrés Sanchez Alberti, Natacha Cerny, Lucas Fabian, Celina Morales, César A N Catalán, Emilio L Malchiodi, Silvia I Cazorla, Valeria P Sülsen

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
2.8field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 31 citations in OpenAlex.

  1. Phenotypic Analysis of the Anti-Molecules (Basel, Switzerland) · 2026
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  6. Extracts and Terpenoids fromMolecules (Basel, Switzerland) · 2024
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  9. Anti-Pharmaceutics · 2023
    Article
  10. Anthelmintic activity ofParasitology · 2022
    Article
  11. Article
  12. Plant Terpenoids as Hit Compounds against Trypanosomiasis.Pharmaceuticals (Basel, Switzerland) · 2022
    Review
  13. ACS omega · 2022
    Article
  14. Antiparasitic Effects of Asteraceae Species Extracts onEvidence-based complementary and alternative medicine : eCAM · 2022
    Article
  15. Molecules (Basel, Switzerland) · 2021
    Review
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Orlando G ElsoInstituto de Química y Metabolismo del Fármaco (IQUIMEFA), CONICET-Universidad de Buenos Aires, Junín 956 2° floor, Buenos Aires 1113, Argentina.
Augusto E BivonaCátedra de Inmunología, Facultad de Farmacia y Bioquímica, Universidad de Buenos Aires, Junín 956 4° floor, Buenos Aires 1113, Argentina.
Andrés Sanchez AlbertiCátedra de Inmunología, Facultad de Farmacia y Bioquímica, Universidad de Buenos Aires, Junín 956 4° floor, Buenos Aires 1113, Argentina.ORCID 0000-0001-5369-2889
Natacha CernyInstituto de Ecología y Desarrollo Sustentable (INEDES), CONICET-Universidad Nacional de Luján, Ruta 5 y Avenida Constitución, Luján 6700, Argentina.
Lucas FabianInstituto de Química y Metabolismo del Fármaco (IQUIMEFA), CONICET-Universidad de Buenos Aires, Junín 956 2° floor, Buenos Aires 1113, Argentina.
Celina MoralesDepartamento de Patología, Instituto de Fisiopatología Cardiovascular, Universidad de Buenos Aires, Facultad de Medicina, Buenos Aires 1113, Argentina.
César A N CatalánInstituto de Química del Noroeste-CONICET (INQUINOA), CONICET-Universidad Nacional de Tucumán, Ayacucho 471, San Miguel de Tucumán T4000INI, Argentina.
Emilio L MalchiodiCátedra de Inmunología, Facultad de Farmacia y Bioquímica, Universidad de Buenos Aires, Junín 956 4° floor, Buenos Aires 1113, Argentina.ORCID 0000-0001-7501-3330
Silvia I CazorlaInstituto de Microbiología y Parasitología Médica-CONICET (IMPaM), Facultad de Medicina, CONICET-Universidad de Buenos Aires, Paraguay 2155. 13° floor, Buenos Aires C1121ABG, Argentina.
Valeria P SülsenInstituto de Química y Metabolismo del Fármaco (IQUIMEFA), CONICET-Universidad de Buenos Aires, Junín 956 2° floor, Buenos Aires 1113, Argentina.
Consejo Nacional de Investigaciones Científicas y Técnicas · ARNational University of Tucumán · ARUniversidad de Buenos Aires · AR

Funding

Agencia Nacional de Promoción Científica y Tecnológica PICT-2014-0854Agencia Nacional de Promoción Científica y Tecnológica PICT 2015-3531Consejo Nacional de Investigaciones Científicas y Técnicas 11220150100158COConsejo Nacional de Investigaciones Científicas y Técnicas PUE-0017CO-2016Universidad de Buenos Aires 20020130100788BAUniversidad de Buenos Aires 20020170100316BA
6 · The paper itself

Abstract

The sesquiterpene lactones eupatoriopicrin, estafietin, eupahakonenin B and minimolide have been isolated from Argentinean Astearaceae species and have been found to be active against

Indexed as

AnimalsAsteraceaeChagas DiseaseHumansLactonesMiceMolecular StructureParasitic Sensitivity TestsPhytochemicalsPlant ExtractsSensitivity and SpecificitySesquiterpenesTrypanocidal AgentsTrypanosoma cruziLactonesPhytochemicalsPlant ExtractsSesquiterpenesTrypanocidal AgentsAsteraceaeMikania spp.sesquiterpene lactonesStevia spp.Trypanosoma cruzi

Identifiers

PMID32344932
PMCPMC7248990
OpenAlexW3017584156

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.