Evidence map›Paper›PMID 32345713›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2020

Is there an antagonistic pleiotropic effect of a

Deng-Feng Zhang, Dong Wang, Yu-Ye Li, Yong-Gang Yao

Open access · bronzeAbstract readLetterComment
PubMed Full text at PMC Publisher
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.1field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 8 citations in OpenAlex.

  1. Tissue-specific transcriptional epistasis between Prkn and Lrrk2 during mycobacterial infection.Mammalian genome : official journal of the International Mammalian Genome Society · 2026
    Article
  2. Review
  3. Article
  4. Article
  5. Review
  6. Reply to Zhang et al.: The differential role of LRRK2 variants in nested leprosy phenotypes.Proceedings of the National Academy of Sciences of the United States of America · 2020
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 2 countries.

Deng-Feng ZhangKey Laboratory of Animal Models and Human Disease Mechanisms of the Chinese Academy of Sciences & Yunnan Province, Kunming Institute of Zoology, Kunming 650223, China; yaoyg@mail.kiz.ac.cn zhangdengfeng@mail.kiz.ac.cn.ORCID 0000-0002-0777-5859
Dong WangKey Laboratory of Animal Models and Human Disease Mechanisms of the Chinese Academy of Sciences & Yunnan Province, Kunming Institute of Zoology, Kunming 650223, China.
Yu-Ye LiDepartment of Dermatology, First Affiliated Hospital of Kunming Medical University, Kunming 650032, China.
Yong-Gang YaoKey Laboratory of Animal Models and Human Disease Mechanisms of the Chinese Academy of Sciences & Yunnan Province, Kunming Institute of Zoology, Kunming 650223, China; yaoyg@mail.kiz.ac.cn zhangdengfeng@mail.kiz.ac.cn.ORCID 0000-0002-2955-0693
Kunming Institute of Zoology · CNKunming Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

LeprosyParkinson DiseaseHumansLeucine-Rich Repeat Serine-Threonine Protein Kinase-2MutationUbiquitin-Protein LigasesLeucine-Rich Repeat Serine-Threonine Protein Kinase-2LRRK2 protein, humanUbiquitin-Protein Ligases

Identifiers

PMID32345713
PMCPMC7229648
OpenAlexW3019040078

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.