Evidence map›Paper›PMID 32356137›Full record

Observational studyInternal and emergency medicine2021

Association between anemia and outcome in patients hospitalized for acute heart failure syndromes: findings from Beijing Acute Heart Failure Registry (Beijing AHF Registry).

Shao-Dong Ye, Si-Jia Wang, Guo-Gan Wang, Lin Li, Zhi-Wei Huang, Jian Qin, Chun-Sheng Li, Xue-Zhong Yu, Hong Shen, Li-Pei Yang and 8 more

Abstract readMulticenter StudyObservational Study
PubMed Publisher
In one paragraph

Observational study in Internal and emergency medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 4 pooled it
2.5field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 4 syntheses or guidelines pooled it, 36 citations in OpenAlex.

  1. Pooled it
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

18 authors at 10 institutions in 1 country.

Shao-Dong Ye *National Center for Cardiovascular Diseases, Fuwai Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, No. 167 Beilishi Road, Xicheng District, Beijing, 100037, China. lilinpumc@sina.com.
Si-Jia Wang *National Center for Cardiovascular Diseases, Fuwai Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, No. 167 Beilishi Road, Xicheng District, Beijing, 100037, China.
Guo-Gan WangNational Center for Cardiovascular Diseases, Fuwai Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, No. 167 Beilishi Road, Xicheng District, Beijing, 100037, China. wangguoganfuwai@163.com.
Lin LiNational Center for Cardiovascular Diseases, Fuwai Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, No. 167 Beilishi Road, Xicheng District, Beijing, 100037, China.
Zhi-Wei HuangNational Center for Cardiovascular Diseases, Fuwai Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, No. 167 Beilishi Road, Xicheng District, Beijing, 100037, China.
Jian QinDepartment of Emergency, Xuanwu Hospital, Capital Medical University, Beijing, 100053, China.
Chun-Sheng LiDepartment of Emergency, Beijing Chao Yang Hospital, Capital Medical University, Beijing, 100020, China.
Xue-Zhong YuDepartment of Emergency, Peking Union Medical College Hospital, Beijing, 100032, China.
Hong ShenDepartment of Emergency, Chinese People's Liberation Army General Hospital, Medical School of Chinese People's Liberation Army, Beijing, 100853, China.
Li-Pei YangDepartment of Emergency, Beijing Friendship Hospital, Capital Medical University, Beijing, 100050, China.
Yan FuDepartment of Emergency, Beijing Tongren Hospital, Capital Medical University, Beijing, 100730, China.
Ya-An ZhengDepartment of Emergency, Peking University Third Hospital, Beijing, 100083, China.
Bin ZhaoDepartment of Emergency, Beijing Jishuitan Hospital, Beijing, 100035, China.
Dong-Min YuDepartment of Emergency, Beijing Tiantan Hospital, Capital Medical University, Beijing, 100050, China.
Fu-Jun QinDepartment of Emergency, Liangxiang Hospital of Fangshan District, Beijing, 102400, China.
De-Gui ZhouDepartment of Emergency, Shunyi District Hospital, Beijing, 101300, China.
Ying LiDepartment of Emergency, People's Hospital of Beijing Daxing District, Beijing, 102600, China.
Fu-Jun LiuDepartment of Emergency, Beijing Luhe Hospital, Capital Medical University, Beijing, 101100, China.
Capital Medical University · CNChinese Academy of Medical Sciences & Peking Union Medical College · CNPeking University · CNBeijing Luhe Hospital Affiliated to Capital Medical University · CNBeijing Tongren Hospital · CNChinese People's Liberation Army · CNPeking Union Medical College Hospital · CNShaoxing People's Hospital · CNShunyi Hospital of Beijing Traditional Chinese Medicine Hospital · CNTang Hospital · CN

Funding

Capital Health Development Research Fund(CN) No.2009-SHF04
6 · The paper itself

Abstract

Whether the anemia increases the risk of mortality in patients with acute heart failure (AHF) remains unclear. This study aims to explore the relationship between anemia and outcomes in patients with AHF including subgroup analysis. This study included 3279 patients with hemoglobin available from the Beijing Acute Heart Failure Registry (Beijing AHF Registry) study. The primary endpoint was all-cause mortality in 1 year, and the secondary endpoint was 1-year all-cause events including all-cause death and readmission. Logistic regression models were applied to describe related variables of anemia in patients with AHF. Multivariate Cox proportional hazards models described associations of anemia with clinical outcomes in the overall cohort and subgroups. 45.4% of the patients were found anemic. They were older and had more comorbidities than non-anemic patients. Variables including older age, female, chronic kidney dysfunction (CKD), lower hematocrit, lower albumin, with loop diuretics applied, without beta-blockers, angiotensin-converting enzyme inhibitors /angiotensin receptor blockers (ACEIs/ARBs) and spironolactone applied in the emergency department (ED) were associated with anemia in AHF patients. Anemic patients had higher 1-year mortality (38.4% vs. 27.2%, p < 0.0001) and 1-year events rates (63.2% vs. 56.7%, p < 0.0001). After adjusted for covariates, anemia was associated with the increase of 1-year mortality (hazard ratio [HR] 1.278; 95% confidence interval [CI] 1.114-1.465; p = 0.0005) and 1-year events (HR 1.136; 95% CI 1.025-1.259; p = 0.0154). The severer anemia patients had higher risks both of 1-year mortality and events. In the subgroup analysis, the independent associations of anemia with 1-year mortality were shown in the subgroups including age < 75 years, male, body mass index < 25 kg/m

Indexed as

AgedAged, 80 and overAnemiaBeijingCause of DeathFemaleHeart FailureHospitalizationHumansMaleMiddle AgedProspective StudiesRegistriesSyndromeAcute heart failureAnemiaMortalityPrevalencePrognosis

Identifiers

PMID32356137
OpenAlexW3021241746

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.