Evidence map›Paper›PMID 32363188›Full record

ArticleFrontiers in bioengineering and biotechnology2020

Angiogenic Potential of Tissue Engineered Cartilage From Human Mesenchymal Stem Cells Is Modulated by Indian Hedgehog and Serpin E1.

Yannick Nossin, Eric Farrell, Wendy J L M Koevoet, Rodrigo A Somoza, Arnold I Caplan, Bent Brachvogel, Gerjo J V M van Osch

Open access · goldAbstract read
In one paragraph

Article in Frontiers in bioengineering and biotechnology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.9field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 18 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 3 countries.

Yannick NossinDepartment of Otorhinolaryngology, Head and Neck Surgery, Erasmus MC, University Medical Center, Rotterdam, Netherlands.
Eric FarrellDepartment of Oral and Maxillofacial Surgery, Erasmus MC, University Medical Center, Rotterdam, Netherlands.
Wendy J L M KoevoetDepartment of Otorhinolaryngology, Head and Neck Surgery, Erasmus MC, University Medical Center, Rotterdam, Netherlands.
Rodrigo A SomozaDepartment of Biology, Skeletal Research Center, Case Western Reserve University, Cleveland, OH, United States.
Arnold I CaplanDepartment of Biology, Skeletal Research Center, Case Western Reserve University, Cleveland, OH, United States.
Bent BrachvogelDepartment of Pediatrics and Adolescent Medicine, Experimental Neonatology, Faculty of Medicine, University of Cologne, Cologne, Germany.
Gerjo J V M van OschDepartment of Otorhinolaryngology, Head and Neck Surgery, Erasmus MC, University Medical Center, Rotterdam, Netherlands.
Erasmus MC · NLCase Western Reserve University · USUniversity of Cologne · DE

Funding

TR&D-4: Growing Tissue in the Scalable, Modular, Automated, and Closed (SMAC) FoundryP41EB021911 · NIBIB · CASE WESTERN RESERVE UNIVERSITY · PI JEAN F WELTER · 2016 to 2026
$13.9M
NIBIB NIH HHS P41 EB021911
6 · The paper itself

Abstract

With rising demand for cartilage tissue repair and replacement, the differentiation of mesenchymal stem cells (BMSCs) into cartilage tissue forming cells provides a promising solution. Often, the BMSC-derived cartilage does not remain stable and continues maturing to bone through the process of endochondral ossification

Indexed as

angiogenesisBMSCchondrogenesisIHHmicroarraysecretomeSerpinE1VEGFa

Identifiers

PMID32363188
PMCPMC7180203
OpenAlexW3015604936

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.