Evidence map›Paper›PMID 32367802›Full record

ArticleeLife2020

Jodie A Schiffer, Francesco A Servello, William R Heath, Francis Raj Gandhi Amrit, Stephanie V Stumbur, Matthias Eder, Olivier Mf Martin, Sean B Johnsen, Julian A Stanley, Hannah Tam and 8 more

Open access · goldAbstract read
In one paragraph

Article in eLife, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
2.1field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 29 citations in OpenAlex.

  1. Article
  2. Hyperactive 20Science advances · 2025
    Article
  3. Article
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  7. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors at 4 institutions in 2 countries.

Jodie A SchifferBiology Department, Northeastern University, Boston, United States.
Francesco A ServelloBiology Department, Northeastern University, Boston, United States.
William R HeathBiology Department, Northeastern University, Boston, United States.
Francis Raj Gandhi AmritDepartment of Pediatrics, University of Pittsburgh School of Medicine, Pittsburgh, United States.
Stephanie V StumburBiology Department, Northeastern University, Boston, United States.
Matthias EderCentre for Genomic Regulation (CRG), The Barcelona Institute of Science and Technology, Barcelona, Spain.
Olivier Mf MartinCentre for Genomic Regulation (CRG), The Barcelona Institute of Science and Technology, Barcelona, Spain.
Sean B JohnsenBiology Department, Northeastern University, Boston, United States.
Julian A StanleyBiology Department, Northeastern University, Boston, United States.ORCID 0000-0002-9193-3791
Hannah TamBiology Department, Northeastern University, Boston, United States.
Sarah J BrennanBiology Department, Northeastern University, Boston, United States.
Natalie G McGowanBiology Department, Northeastern University, Boston, United States.
Abigail L VogelaarBiology Department, Northeastern University, Boston, United States.
Yuyan XuBiology Department, Northeastern University, Boston, United States.
William T SerkinBiology Department, Northeastern University, Boston, United States.
Arjumand GhaziDepartment of Pediatrics, University of Pittsburgh School of Medicine, Pittsburgh, United States.
Nicholas StroustrupCentre for Genomic Regulation (CRG), The Barcelona Institute of Science and Technology, Barcelona, Spain.ORCID 0000-0001-9530-7301
Javier ApfeldBiology Department, Northeastern University, Boston, United States.ORCID 0000-0001-9897-5671
Boston University · USCentre for Genomic Regulation · ESUniversity of Pittsburgh · USUniversitat Pompeu Fabra · ES

Funding

Enhancing and expanding the CGC Strain CollectionP40OD010440 · OD · UNIVERSITY OF MINNESOTA · PI Aric L Daul, Ann E. Rougvie · 2012 to 2026
$7.5M
The Coordination of Lipid Synthesis and Breakdown in Metabolism and AgingR01AG051659 · NIA · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI GHAZI, ARJUMAND · 2016 to 2019
$1.6M
Role of the transcription elongation and splicing factor TCER-1 in repressing immunity and promoting fertilityR56AG066682 · NIA · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI GHAZI, ARJUMAND · 2021 to 2021
$321k
NIA NIH HHS R01 AG051659NIA NIH HHS R56 AG066682NIH HHS P40 OD010440
6 · The paper itself

Abstract

Hydrogen peroxide is the preeminent chemical weapon that organisms use for combat. Individual cells rely on conserved defenses to prevent and repair peroxide-induced damage, but whether similar defenses might be coordinated across cells in animals remains poorly understood. Here, we identify a neuronal circuit in the nematode

Indexed as

AnimalsCaenorhabditis elegansCaenorhabditis elegans ProteinsCatalepsyEscherichia coliHydrogen PeroxideInsulin-Like Growth Factor ISensory Receptor CellsSignal TransductionTransforming Growth Factor betaCaenorhabditis elegans ProteinsDAF-7 protein, C elegansHydrogen PeroxideInsulin-Like Growth Factor ITransforming Growth Factor betaC. elegansdevelopmental biologyE. colihydrogen peroxideinsulin signalingneurosciencesensory perceptionstress responseTGFβ signaling

Identifiers

PMID32367802
PMCPMC7213980
OpenAlexW3023189049

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.