Evidence map›Paper›PMID 32372179›Full record

SynthesisJournal of the Egyptian National Cancer Institute2020

Hepatocellular Carcinoma (HCC) in Egypt: A comprehensive overview.

Wafaa M Rashed, Mohamed Ahmed Mohamed Kandeil, Mohamed O Mahmoud, Sameera Ezzat

4 registry-linked trialsAbstract readComparative StudySystematic Review
In one paragraph

Synthesis in Journal of the Egyptian National Cancer Institute, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 4 registered trials, which are not on this map. Cited by 97 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
97citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04767750 completednot on this map

Role of LncRNA H19 in The Regulation of IGF-1R Expression: A Possible Association Between Type 2 Diabetes and Hepatocellular Carcinoma

TypeobservationalSponsorMansoura UniversityRan2020 to 2022Enrolled101ConditionsHepatocellular Carcinoma, Type 2 Diabetes, CancerArmsBlood sample collection
NCT05291338 completednot on this mapstarted 2022, after this paper: background citation

Pharmacogenetic Study in Hepatocellular Carcinoma Patients Underwent TACE

TypeobservationalSponsorRehab WeridaRan2022 to 2023Enrolled107ConditionsHepatocellular CarcinomaArmsDoxorubicin, Lipiodol
NCT05568576 completednot on this map

Metabolic Syndrome and Long-term Survival Following Liver Resection for Hepatocellular Carcinoma Among Patients With Chronic Hepatitis C Virus Infection

TypeobservationalSponsorAssiut UniversityRan2015 to 2022Enrolled70ConditionsSurvival
NCT06544005 completednot on this mapstarted 2022, after this paper: background citation

Implication of Long Non-coding RNA HOTTIP Haplotype

TypeobservationalSponsorAin Shams UniversityRan2022 to 2024Enrolled198ConditionsHepatocellular Carcinoma
3 · Its place in the literature

Who cites it

97 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
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  4. Review
  5. Article
  6. Review
  7. Article
  8. Article
  9. Article
  10. Article
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  12. Article
  13. Role of miR-15b and miR-130b as Non-Invasive Biomarkers in Hepatocellular Carcinoma.Asian Pacific journal of cancer prevention : APJCP · 2025
    Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Review

37 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Wafaa M RashedDepartment of Research, Children's Cancer Hospital-57357, Cairo, Egypt. wafaaanor@gmail.com.ORCID http://orcid.org/0000-0001-7531-2840
Mohamed Ahmed Mohamed KandeilDepartment of Biochemistry, Faculty of Veterinary Medicine, Beni-Suef University, Beni-Suef, Egypt.
Mohamed O MahmoudDepartment of Biochemistry, Faculty of Pharmacy, Beni-Suef University, Beni-Suef, Egypt.
Sameera EzzatDepartment of Epidemiology and Prevention Medicine, National Liver Institute, Menoufia University, Menoufia, Egypt.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundWorldwide, hepatocellular carcinoma (HCC) is a universal problem and its epidemiological data showed variation from place to place. Hepatocellular carcinoma (HCC) is the sixth and fourth common cancer in worldwide and Egypt, respectively. Egypt ranks the third and 15 MAIN BODY: The risk factors for HCC in Egypt are of great importance to be reported. The risk factor for HCC are either environmental- or host/genetic-related risk factors. In the last years, there is a tangible improvement of both screening and surveillance strategies of HCC in Egypt. The unprecedented national screening campaign launched by the end of 2018 is a mirror image of this improvement. While the improvement of the HCC prevention requires the governmental health administration to implement health policies. Although the diagnosis of Egyptian HCC patients follows the international guidelines but HCC treatment options are limited in terms of cost. In addition, there are limited Egyptian reports about HCC survival and relapse. Both basic and clinical HCC research in Egypt are still limited compared to worldwide. SHORT

conclusionDeep analysis and understanding of factors affecting HCC burden variation worldwide help in customization of efforts exerted to face HCC in different countries especially large country like Egypt. Overall, the presence of a research strategy to fight HCC in Egyptian patients will help in the optimum allocation of available resources to reduce the numbers of HCC cases and deaths and to improve the quality of life.

Indexed as

Carcinoma, HepatocellularEarly Detection of CancerEgyptEmigration and ImmigrationGlobal Burden of DiseaseHumansLiver NeoplasmsMass ScreeningNeoplasm Recurrence, LocalRisk FactorsDiagnosis and treatmentEpidemiologyHepatocellular carcinomaPreventionResearchScreening and Surveillance

Identifiers

PMID32372179
PMCPMC13325438

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.