ArticleFrontiers in genetics2020
The Role of Genetic Variation of BMI, Body Composition, and Fat Distribution for Mental Traits and Disorders: A Look-Up and Mendelian Randomization Study.
Article in Frontiers in genetics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 3 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
17 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Socioeconomic position, genetic susceptibility, and epigenetic profiles in obesity across the life course: a systematic review.International journal of obesity (2005) · 2026Pooled it
- Investigating the shared genetic architecture between schizophrenia and body mass index.Molecular psychiatry · 2023Pooled it
- Applications of Mendelian randomization in psychiatry: a comprehensive systematic review.Psychiatric genetics · 2022Pooled it
- Fat-brain axis indicated by mutual impacts between body fat and brain phenotypes.Journal of translational medicine · 2025Article
- Evaluating the Significance of Obesity or Excessive Weight in Various Mental Health Disorders: A Systematic Review.Cureus · 2025Review
- Childhood psychosocial adjustment and midlife obesity, diabetes and hypertension: prospective study from two birth cohorts.The British journal of psychiatry : the journal of mental science · 2024Article
- Obesity-associated factors in psychiatric outpatients: A multicenter questionnaire survey.Neuropsychopharmacology reports · 2024Article
- Association between increased BMI and cognitive function in first-episode drug-naïve male schizophrenia.Frontiers in psychiatry · 2024Article
- Anxiety, depression, and their comorbidity among Chinese college students during the COVID-19 lockdown in the post-epidemic era: an online cross-sectional survey.BMC psychiatry · 2023Article
- Characterizing the Shared Genetic Underpinnings of Schizophrenia and Cardiovascular Disease Risk Factors.The American journal of psychiatry · 2023Article
- Childhood attention-deficit hyperactivity disorder problems and mid-life cardiovascular risk: prospective population cohort study.The British journal of psychiatry : the journal of mental science · 2023Article
- Analyzing histone ChIP-seq data with a bin-based probability of being signal.PLoS computational biology · 2023Article
- Amplitudes of resting-state functional networks - investigation into their correlates and biophysical properties.NeuroImage · 2023Article
- Exploring Lead loci shared between schizophrenia and Cardiometabolic traits.BMC genomics · 2022Article
- A Causal Relationship between Vitamin C Intake with Hyperglycemia and Metabolic Syndrome Risk: A Two-Sample Mendelian Randomization Study.Antioxidants (Basel, Switzerland) · 2022Article
- Disentangling sex differences in the shared genetic architecture of posttraumatic stress disorder, traumatic experiences, and social support with body size and composition.Neurobiology of stress · 2021Article
- Impact of Psychotropic Medication Effects on Obesity and the Metabolic Syndrome in People With Serious Mental Illness.Frontiers in endocrinology · 2020Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Anthropometric traits and mental disorders or traits are known to be associated clinically and to show genetic overlap. We aimed to identify genetic variants with relevance for mental disorders/traits and either (i) body mass index (or obesity), (ii) body composition, (and/or) (iii) body fat distribution. We performed a look-up analysis of 1,005 genome-wide significant SNPs for BMI, body composition, and body fat distribution in 15 mental disorders/traits. We identified 40 independent loci with one or more SNPs fulfilling our threshold significance criterion (
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.