Evidence map›Paper›PMID 32374641›Full record

ArticleMolecular biology of the cell2020

Redox signaling modulates Rho activity and tissue contractility in the

Charlotte A Kelley, Sasha De Henau, Liam Bell, Tobias B Dansen, Erin J Cram

Open access · greenAbstract read
In one paragraph

Article in Molecular biology of the cell, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.5field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Charlotte A KelleyDepartment of Biology, Northeastern University, Boston, MA 02115.
Sasha De HenauCenter for Molecular Medicine, Molecular Cancer Research Section, University Medical Center Utrecht, Universiteitsweg 100, 3584 CG Utrecht, the Netherlands.
Liam BellDepartment of Biology, Northeastern University, Boston, MA 02115.
Tobias B DansenCenter for Molecular Medicine, Molecular Cancer Research Section, University Medical Center Utrecht, Universiteitsweg 100, 3584 CG Utrecht, the Netherlands.
Erin J CramDepartment of Biology, Northeastern University, Boston, MA 02115.
Northeastern University · USUniversity Medical Center Utrecht · NL

Funding

Enhancing and expanding the CGC Strain CollectionP40OD010440 · OD · UNIVERSITY OF MINNESOTA · PI Aric L Daul, Ann E. Rougvie · 2012 to 2026
$7.5M
In vivo analysis of mechanotransductionR01GM110268 · NIGMS · NORTHEASTERN UNIVERSITY · PI CRAM, ERIN JEAN · 2014 to 2023
$2.8M
National Science Foundation 1757443National Science Foundation 1816640NIGMS NIH HHS R01 GM110268NIH HHS P40 OD010440
6 · The paper itself

Abstract

Actomyosin-based contractility in smooth muscle and nonmuscle cells is regulated by signaling through the small GTPase Rho and by calcium-activated pathways. We use the myoepithelial cells of the

Indexed as

Actin CytoskeletonActomyosinAnimalsCaenorhabditis elegansCaenorhabditis elegans ProteinsCalciumEpithelial CellsHydrogen PeroxideMuscle CellsMuscle ContractionMuscle, SmoothOxidation-Reductionrho-Associated Kinasesrho GTP-Binding ProteinsSignal TransductionSuperoxide DismutaseActomyosinCaenorhabditis elegans ProteinsCalciumHydrogen Peroxiderho-Associated Kinasesrho GTP-Binding ProteinsSuperoxide Dismutase

Identifiers

PMID32374641
PMCPMC7359568
OpenAlexW3022607448

What Socratic holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.