Evidence mapPaperPMID 32386911Full record

GuidelineGynecologic oncology2020

Anti-cancer therapy and clinical trial considerations for gynecologic oncology patients during the COVID-19 pandemic crisis.

Bhavana Pothuri, Angeles Alvarez Secord, Deborah K Armstrong, John Chan, Amanda N Fader, Warner Huh, Joshua Kesterson, Joyce F Liu, Kathleen Moore, Shannon N Westin and 1 more

Abstract readPractice Guideline
In one paragraph

Guideline in Gynecologic oncology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed.

  1. Review
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  6. Article
  7. Impact of the COVID-19 pandemic on training conditions and education in oncologic disciplines: a survey-based analysis.Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al] · 2023
    Article
  8. Article
  9. Article
  10. Article
  11. Being in touch: narrative assessment of patients receiving online integrative oncology treatments during COVID-19.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2021
    Article
  12. Article
  13. Article
  14. Review
  15. Article
  16. Observational
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  18. Observational
  19. Article
  20. Alternative management for gynecological cancer care during the COVID-2019 pandemic: A Latin American survey.International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Bhavana PothuriNYU Langone Health, Perlmutter Cancer Center, New York University School of Medicine, New York, NY, United States. Electronic address: Bhavana.Pothuri@nyulangone.org.
Angeles Alvarez SecordDuke Cancer Institute, Duke University Health System, Durham, NC, United States.
Deborah K ArmstrongKelly Gynecologic Oncology Service, Department of Gynecology and Obstetrics, Johns Hopkins School of Medicine, Baltimore, MD, United States.
John ChanCalifornia Pacific-Palo Alto Medical Foundation, Sutter Research Institute, San Francisco, CA, United States.
Amanda N FaderKelly Gynecologic Oncology Service, Department of Gynecology and Obstetrics, Johns Hopkins School of Medicine, Baltimore, MD, United States.
Warner HuhUniversity of Alabama at Birmingham, Birmingham, AL, United States.
Joshua KestersonPenn State Hershey Medical Center, Hershey, PA, United States.
Joyce F LiuDana-Farber Cancer Institute, Boston, MA, United States.
Kathleen MooreUniversity of Oklahoma, Stephenson Cancer Center, Oklahoma City, OK, United States.
Shannon N WestinUniversity of Texas, MD Anderson Cancer Center, Houston, TX, United States.
R Wendel NaumannLevine Cancer Center, Atrium Health, Charlotte, NC, United States.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesThe COVID-19 pandemic has consumed considerable resources and has impacted the delivery of cancer care. Patients with cancer may have factors which place them at high risk for COVID 19 morbidity or mortality. Highly immunosuppressive chemotherapy regimens and possible exposure to COVID-19 during treatment may put patients at additional risk. The Society of Gynecologic Oncology convened an expert panel to address recommendations for best practices during this crisis to minimize risk to patients from deviations in cancer care and from COVID-19 morbidity.

methodsAn expert panel convened to develop initial consensus guidelines regarding anti-neoplastic therapy during the COVID-19 pandemic with respect to gynecologic cancer care and clinical trials.

resultsCOVID-19 poses special risks to patients who are older, have medical co-morbidities, and cancer. In addition, this pandemic will likely strain resources, making delivery of cancer care or conduct of clinical trials unpredictable. Recommendations are to limit visits and contact with health care facilities by using telemedicine when appropriate, and choosing regimens which require less frequent visits and which are less immunosuppressive. Deviations will occur in clinical trials as a result of limited resources, and it is important to understand regulatory obligations to trial sponsors as well as to the IRB to ensure that clinical trial and patient safety oversight are maintained.

conclusionsThe ongoing crisis will strain resources needed to deliver cancer care. When alterations to the delivery of care are mandated, efforts should be taken to minimize risks and maximize safety while approximating standard practice.

Indexed as

Clinical Trials as TopicCoronavirus InfectionsCOVID-19FemaleGenital Neoplasms, FemaleHumansMedical OncologyPandemicsPneumonia, ViralRandomized Controlled Trials as Topic

Identifiers

PMID32386911
PMCPMC7177100

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.